Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer - sprookjes - yvandenbroek - TriplyDB

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

http://www.wikidata.org/entity/Q37277677

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Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells Aptamers in Therapeutics Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers Aptamers: A promising chemical antibody for cancer therapy Recent Developments in Active Tumor Targeted Multifunctional Nanoparticles for Combination Chemotherapy in Cancer Treatment and Imaging Progress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery Systems Aptamer for imaging and therapeutic targeting of brain tumor glioblastoma Nucleic acid aptamers: an emerging frontier in cancer therapy Oligonucleotide Therapies: The Past and the Present Co-development of diagnostic vectors to support targeted therapies and theranostics: essential tools in personalized cancer therapy Smart functional nucleic acid chimeras: enabling tissue specific RNA targeting therapy Monomer-dimer equilibrium for the 5'-5' stacking of propeller-type parallel-stranded G-quadruplexes: NMR structural study Methuosis: nonapoptotic cell death associated with vacuolization of macropinosome and endosome compartments.Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses Development of Cell-SELEX Technology and Its Application in Cancer Diagnosis and Therapy Therapeutic aptamers: developmental potential as anticancer drugs RSV fusion: time for a new model RNA-binding protein nucleolin in disease Aptamer-Drug Conjugates General cell-binding activity of intramolecular G-quadruplexes with parallel structure Finding and characterizing the complexes of drug like molecules with quadruplex DNA: combined use of an enhanced hydroxyl radical cleavage protocol and NMR A Synthetic Aptamer-Drug Adduct for Targeted Liver Cancer Therapy RNA plasticity and selectivity applicable to therapeutics and novel biosensor development Bioactivity of 2'-deoxyinosine-incorporated aptamer AS1411 Nucleic Acid Aptamers as Potential Therapeutic and Diagnostic Agents for Lymphoma.Vascular endothelial growth factor as an anti-angiogenic target for cancer therapy Aptamers and their biological applications Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides.SL2B aptamer and folic acid dual-targeting DNA nanostructures for synergic biological effect with chemotherapy to combat colorectal cancer.Improved in vitro efficacy of gold nanoconstructs by increased loading of G-quadruplex aptamer.Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization.Selection of Nucleic Acid Aptamers Targeting Tumor Cell-Surface Protein Biomarkers Cell-type-specific, Aptamer-functionalized Agents for Targeted Disease Therapy G-quadruplex structure of an anti-proliferative DNA sequence.Structural insights into G-quadruplexes: towards new anticancer drugs.Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy.Nucleic acid aptamers: clinical applications and promising new horizons Nucleolin promotes in vitro translation of feline calicivirus genomic RNA.Probing high affinity sequences of DNA aptamer against VEGF165

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Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

http://www.wikidata.org/entity/Q37277677

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 20 January 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Discovery and development of t ...... s a novel treatment for cancer

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Discovery and development of t ...... a novel treatment for cancer.

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type

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Discovery and development of t ...... s a novel treatment for cancer

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Discovery and development of t ...... a novel treatment for cancer.

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prefLabel

Discovery and development of t ...... s a novel treatment for cancer

@en

Discovery and development of t ...... a novel treatment for cancer.

@nl

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J.YEXMP.2009.01.004

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Experimental and Molecular Pathology

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Discovery and development of t ...... s a novel treatment for cancer

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Damian A Laber

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Donald M Miller

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John O Trent

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Paula J Bates

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Shelia D Thomas

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P2860

The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin

Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n

Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes

Phosphodiester CpG oligonucleotides as adjuvants: polyguanosine runs enhance cellular uptake and improve immunostimulative activity of phosphodiester CpG oligonucleotides in vitro and in vivo

Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA

The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptor

Major cell surface-located protein substrates of an ecto-protein kinase are homologs of known nuclear proteins

Discovery and development of anticancer aptamers

Cellular adhesion mediated by factor J, a complement inhibitor. Evidence for nucleolin involvement

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151-164

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scholarly article

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10.1016/J.YEXMP.2009.01.004

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3

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2009-01-20T00:00:00Z

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19454272

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2716701

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