Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.
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The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines.The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrestAn oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cellsCyclin B1 overexpression induces cell death independent of mitotic arrest.MCPIP1 Selectively Destabilizes Transcripts Associated with an Antiapoptotic Gene Expression Program in Breast Cancer Cells That Can Elicit Complete Tumor Regression.Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs.Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells.Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death.Molecular analysis of functional redundancy among anti-apoptotic Bcl-2 proteins and its role in cancer cell survivalMitotic arrest-induced phosphorylation of Mcl-1 revisited using two-dimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified.Synergistic induction of apoptosis by a polo-like kinase 1 inhibitor and microtubule-interfering drugs in Ewing sarcoma cells.Molecular Mechanisms by Which a Fucus vesiculosus Extract Mediates Cell Cycle Inhibition and Cell Death in Pancreatic Cancer Cells.Eribulin alone or in combination with the PLK1 inhibitor BI 6727 triggers intrinsic apoptosis in Ewing sarcoma cell lines.Modeling Cancer Cell Growth Dynamics In vitro in Response to Antimitotic Drug TreatmentPolo-like kinase 1 inhibition sensitizes neuroblastoma cells for vinca alkaloid-induced apoptosis.Oncogenic KRAS triggers MAPK-dependent errors in mitosis and MYC-dependent sensitivity to anti-mitotic agents.Small peptide substrates and high resolution peptide gels for the analysis of site-specific protein phosphorylation and dephosphorylation.Advances in the treatment of soft tissue sarcoma: focus on eribulin.Perturbing mitosis for anti-cancer therapy: is cell death the only answer?The impact of phosphatases on proliferative and survival signaling in cancer.Synthetic lethality in CCNE1-amplified high grade serous ovarian cancer through combined inhibition of Polo-like kinase 1 and microtubule dynamics.Universal response in the RKO colon cancer cell line to distinct antimitotic therapies.Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach
P2860
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P2860
Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.
@en
Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.
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type
label
Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.
@en
Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.
@nl
prefLabel
Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.
@en
Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.
@nl
P2093
P2860
P356
P1476
Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death.
@en
P2093
J M Eichhorn
N Sakurikar
S E Alford
T C Chambers
P2860
P356
10.1038/CDDIS.2013.360
P577
2013-10-03T00:00:00Z