T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo.
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Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cellsCo-Stimulatory Blockade of the CD28/CD80-86/CTLA-4 Balance in Transplantation: Impact on Memory T Cells?Update on CD40 and CD154 blockade in transplant modelsImmunosenescence in renal transplantation: a changing balance of innate and adaptive immunityCostimulation of T cellsAn antagonist IL-15/Fc protein prevents costimulation blockade-resistant rejectionEvidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cellsThe relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells.The class III histone deacetylase sirtuin 1 in immune suppression and its therapeutic potential in rheumatoid arthritis.CD28/CTLA-4 and CD80/CD86 families: signaling and function.A randomized controlled trial to evaluate inhibition of T-cell costimulation in allergen-induced airway inflammation.The in vivo mechanism of action of CTLA4IgDevelopment of human T-cell leukemia virus type 1-transformed tumors in rats following suppression of T-cell immunity by CD80 and CD86 blockadeBlocking costimulatory signals to induce transplantation tolerance and prevent autoimmune disease.Inhibition of allorecognition by a human class II MHC-derived peptide through the induction of apoptosis.The B7/CD28/CTLA4 T-cell activation pathway. Implications for inflammatory lung disease.T-cell co-stimulatory blockade in kidney transplantation: back to the benchAn enigmatic tail of CD28 signaling.CTLA4-Ig: a novel immunosuppressive agent.Costimulatory pathways in transplantation.Azathioprine: old drug, new actions.Bone marrow-derived dendritic cell progenitors (NLDC 145+, MHC class II+, B7-1dim, B7-2-) induce alloantigen-specific hyporesponsiveness in murine T lymphocytesRole of interleukin 12 and costimulators in T cell anergy in vivo.PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue.CD160Ig fusion protein targets a novel costimulatory pathway and prolongs allograft survival.Costimulation blockade inhibits the indirect pathway of allorecognition in nerve allograft rejectionPDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection.The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivoMice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsivenessCostimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80dim, CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipientsAntagonistic and agonistic anti-canine CD28 monoclonal antibodies: tools for allogeneic transplantationImmunomodulatory effects induced by cytotoxic T lymphocyte antigen 4 immunoglobulin with donor peripheral blood mononuclear cell infusion in canine major histocompatibility complex-haplo-identical non-myeloablative hematopoietic cell transplantationAdvances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantationSpontaneous allograft tolerance in B7-deficient mice independent of preexisting endogenous CD4+CD25+ regulatory T-cells.Anti-CD28 Antibody-Initiated Cytokine Storm in Canines.T-cell activation and transplantation tolerance.Antiviral immune responses in CTLA4 transgenic mice.Tolerance-inducing strategies in islet transplantationCD28 family and chronic rejection: "to belatacept...And beyond!".Signaling through CD28 and CTLA-4 controls two distinct forms of T cell anergy.
P2860
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P2860
T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
T-cell activation by the CD28 ...... c allograft rejection in vivo.
@en
T-cell activation by the CD28 ...... c allograft rejection in vivo.
@nl
type
label
T-cell activation by the CD28 ...... c allograft rejection in vivo.
@en
T-cell activation by the CD28 ...... c allograft rejection in vivo.
@nl
prefLabel
T-cell activation by the CD28 ...... c allograft rejection in vivo.
@en
T-cell activation by the CD28 ...... c allograft rejection in vivo.
@nl
P2093
P2860
P356
P1476
T-cell activation by the CD28 ...... c allograft rejection in vivo.
@en
P2093
J M Leiden
M L Gibson
P S Linsley
P2860
P304
11102-11105
P356
10.1073/PNAS.89.22.11102
P407
P577
1992-11-01T00:00:00Z