Targeting the PI3K-AKT-mTOR signaling network in cancer.
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CD164 regulates the tumorigenesis of ovarian surface epithelial cells through the SDF-1α/CXCR4 axisPharmacodynamic Biomarker Development for PI3K Pathway TherapeuticsNatural product-based nanomedicine: recent advances and issuesO-GlcNAcylation and Metabolic Reprograming in CancerPAS kinase: a nutrient sensing regulator of glucose homeostasis.Molecular predictive markers in tumors of the gastrointestinal tractGrb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancerIn-vitro and in-vivo combined effect of ARQ 092, an AKT inhibitor, with ARQ 087, a FGFR inhibitor.Pemetrexed induces S-phase arrest and apoptosis via a deregulated activation of Akt signaling pathway.Increasing effect of Tangzhiqing formula on IRS-1-dependent PI3K/AKT signaling in muscle.Role of AKT signaling in DNA repair and clinical response to cancer therapy.Colorectal cancer with liver metastases: neoadjuvant chemotherapy, surgical resection first or palliation alone?IL-32 promotes breast cancer cell growth and invasivenessPAS kinase is activated by direct SNF1-dependent phosphorylation and mediates inhibition of TORC1 through the phosphorylation and activation of Pbp1Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-κB pathway.Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression.Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor.Safety and tolerability of AZD5363 in Japanese patients with advanced solid tumorsHyperglycemia and Phosphatidylinositol 3-Kinase/Protein Kinase B/Mammalian Target of Rapamycin (PI3K/AKT/mTOR) Inhibitors in Phase I Trials: Incidence, Predictive Factors, and ManagementCombining molecular targeted agents with radiation therapy for malignant gliomasPI3K/Akt/mTOR signaling & its regulator tumour suppressor genes PTEN & LKB1 in human uterine leiomyomas.The molecular mechanisms and therapeutic potential of microRNA-7 in cancer.Effects of Ras homolog gene family, member C gene silencing combined with rapamycin on hepatocellular carcinoma cell growth.Thymoquinone Pretreatment Overcomes the Insensitivity and Potentiates the Antitumor Effect of Gemcitabine Through Abrogation of Notch1, PI3K/Akt/mTOR Regulated Signaling Pathways in Pancreatic Cancer.In vitro and in vivo anti-cancer activity of formononetin on human cervical cancer cell line HeLa.MACC1 is involved in the regulation of proliferation, colony formation, invasion ability, cell cycle distribution, apoptosis and tumorigenicity by altering Akt signaling pathway in human osteosarcoma.The Therapeutic Potential of PI3K/Akt/mTOR Inhibitors in Breast Cancer: Rational and Progress.Regulators of Glucose Metabolism in CD4(+) and CD8(+) T Cells.The PI3K/Akt pathway: a critical player in intervertebral disc degeneration.Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo.Molecular targeted agents--where we are and where we are going.Immunohistochemical Analysis of the Activation Status of the Akt/mTOR/pS6 Signaling Pathway in Oral Lichen Planus.CAR-T cells and combination therapies: What's next in the immunotherapy revolution?Predicting and Overcoming Chemotherapeutic Resistance in Breast Cancer.Characterizing genomic differences of human cancer stratified by the TP53 mutation status.Comprehensive genomic profiling aids in treatment of a metastatic endometrial cancer.Immunohistochemical and molecular analysis of PI3K/AKT/mTOR pathway in esophageal carcinoma.DNA Damage Inducible Transcript 4 Gene: The Switch of the Metabolism as Potential Target in Cancer.Phosphoinositide 3-Kinase Signaling Pathway in Pancreatic Ductal Adenocarcinoma Progression, Pathogenesis, and Therapeutics.Fibroblast activation protein in osteosarcoma cells promotes angiogenesis via AKT and ERK signaling pathways.
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Targeting the PI3K-AKT-mTOR signaling network in cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Targeting the PI3K-AKT-mTOR signaling network in cancer.
@en
Targeting the PI3K-AKT-mTOR signaling network in cancer.
@nl
type
label
Targeting the PI3K-AKT-mTOR signaling network in cancer.
@en
Targeting the PI3K-AKT-mTOR signaling network in cancer.
@nl
prefLabel
Targeting the PI3K-AKT-mTOR signaling network in cancer.
@en
Targeting the PI3K-AKT-mTOR signaling network in cancer.
@nl
P2093
P2860
P921
P356
P1476
Targeting the PI3K-AKT-mTOR signaling network in cancer.
@en
P2093
David Cunningham
Khurum H Khan
Timothy A Yap
P2860
P304
P356
10.5732/CJC.013.10057
P5008
P577
2013-05-01T00:00:00Z