about
NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligasesCrossing the line: selection and evolution of virulence traitsTargeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black DeathA draft genome of Yersinia pestis from victims of the Black DeathQuantitative mass spectrometry catalogues Salmonella pathogenicity island-2 effectors and identifies their cognate host binding partnersSalmonella pathogenicity island 2 is expressed prior to penetrating the intestine.CXCL9 contributes to antimicrobial protection of the gut during citrobacter rodentium infection independent of chemokine-receptor signalingTranscriptional priming of Salmonella Pathogenicity Island-2 precedes cellular invasionGogB is an anti-inflammatory effector that limits tissue damage during Salmonella infection through interaction with human FBXO22 and Skp1Characterization of DalS, an ATP-binding Cassette Transporter for D-Alanine, and Its Role in Pathogenesis in Salmonella entericaStructural and biochemical characterization of SrcA, a multi-cargo type III secretion chaperone in Salmonella required for pathogenic association with a hostThe SseC translocon component in Salmonella enterica serovar Typhimurium is chaperoned by SscABacterial genetic determinants of non-O157 STEC outbreaks and hemolytic-uremic syndrome after infection.Molecular analysis as an aid to assess the public health risk of non-O157 Shiga toxin-producing Escherichia coli strains.FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling.RpoE fine tunes expression of a subset of SsrB-regulated virulence factors in Salmonella enterica serovar Typhimurium.A novel inhibitor of Chlamydophila pneumoniae protein kinase D (PknD) inhibits phosphorylation of CdsD and suppresses bacterial replication.Identification of the regulatory logic controlling Salmonella pathoadaptation by the SsrA-SsrB two-component system.Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypesThe non-motile phenotype of Salmonella hha ydgT mutants is mediated through PefI-SrgD.Virulence is positively selected by transmission success between mammalian hosts.Host defense peptide resistance contributes to colonization and maximal intestinal pathology by Crohn's disease-associated adherent-invasive Escherichia coli.Identification of the docking site between a type III secretion system ATPase and a chaperone for effector cargo.Chlamydia pneumoniae and atherosclerosis: does the evidence support a causal or contributory role?Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance.Salmonella evades D-amino acid oxidase to promote infection in neutrophils.Salmonella phage ST64B encodes a member of the SseK/NleB effector familyStrategic targeting of essential host-pathogen interactions in chlamydial disease.SseL is a salmonella-specific translocated effector integrated into the SsrB-controlled salmonella pathogenicity island 2 type III secretion system.Evasive maneuvers by secreted bacterial proteins to avoid innate immune responses.Type VI secretion system-associated gene clusters contribute to pathogenesis of Salmonella enterica serovar TyphimuriumInsertion of the bacterial type III translocon: not your average needle stick.A Highly Effective Component Vaccine against Nontyphoidal Salmonella enterica Infections.Acute Infectious Gastroenteritis Potentiates a Crohn's Disease Pathobiont to Fuel Ongoing Inflammation in the Post-Infectious Period.Convergence of External Crohn's Disease Risk Factors on Intestinal Bacteria.Salmonella enterica serovar Senftenberg human clinical isolates lacking SPI-1.Targeting bacterial secretion systems: benefits of disarmament in the microcosm.Mapping and regulation of genes within Salmonella pathogenicity island 12 that contribute to in vivo fitness of Salmonella enterica Serovar Typhimurium.Role of RpoS in the virulence of Citrobacter rodentiumSalmonella-containing vacuoles display centrifugal movement associated with cell-to-cell transfer in epithelial cells.
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description
hulumtues
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Brian K Coombes
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Brian K Coombes
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P31
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0000-0001-9883-1010