Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells. - sprookjes - yvandenbroek - TriplyDB

Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells.

Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells.

http://www.wikidata.org/entity/Q37415807

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Nucleic acid aptamers: an emerging frontier in cancer therapy Mechanism of regulation of bcl-2 mRNA by nucleolin and A+U-rich element-binding factor 1 (AUF1)General cell-binding activity of intramolecular G-quadruplexes with parallel structure A Synthetic Aptamer-Drug Adduct for Targeted Liver Cancer Therapy Aptamer-conjugated Magnetic Nanoparticles as Targeted Magnetic Resonance Imaging Contrast Agent for Breast Cancer.Kruppel-like factor 4 is a novel mediator of Kallistatin in inhibiting endothelial inflammation via increased endothelial nitric-oxide synthase expression.Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization.Selection of Nucleic Acid Aptamers Targeting Tumor Cell-Surface Protein Biomarkers Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type Nucleolin promotes in vitro translation of feline calicivirus genomic RNA.A nucleolin-DNMT1 regulatory axis in acute myeloid leukemogenesis.A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism Structural requirements for the procoagulant activity of nucleic acids.Aptamer photoregulation in vivo Aptamers: active targeting ligands for cancer diagnosis and therapy Biodistribution and in vivo toxicity of aptamer-loaded gold nanostars.Nucleolin down-regulation is involved in ADP-induced cell cycle arrest in S phase and cell apoptosis in vascular endothelial cells.Cell surface nucleolin facilitates enterovirus 71 binding and infection.Aptamer-labeled PLGA nanoparticles for targeting cancer cells.Human anti-nucleolin recombinant immunoagent for cancer therapy.Direct observation of nanoparticle-cancer cell nucleus interactions.Aptamer-mediated delivery of chemotherapy to pancreatic cancer cells Cotinine-conjugated aptamer/anti-cotinine antibody complexes as a novel affinity unit for use in biological assays.AS1411-conjugated gold nanospheres and their potential for breast cancer therapy Interplay between αvβ3 integrin and nucleolin regulates human endothelial and glioma cell migration.A Targeted DNAzyme-Nanocomposite Probe Equipped with Built-in Zn(2+) Arsenal for Combined Treatment of Gene Regulation and Drug Delivery Study of the Function of G-Rich Aptamers Selected for Lung Adenocarcinoma Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles.Nucleolin interacts with the dengue virus capsid protein and plays a role in formation of infectious virus particles.Overview of the role of nanotechnological innovations in the detection and treatment of solid tumors.Grafting aptamers onto gold nanostars increases in vitro efficacy in a wide range of cancer cell types.Cell-surface nucleolin acts as a central mediator for carcinogenic, anti-carcinogenic, and disease-related ligands.G-quadruplexes: targets and tools in anticancer drug design.Aptamers as targeted therapeutics: current potential and challenges.The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell.Cell-specific aptamers as emerging therapeutics.Aptamer-nanoparticle bioconjugates enhance intracellular delivery of vinorelbine to breast cancer cells.Self-assembled aptamer-based drug carriers for bispecific cytotoxicity to cancer cells DNA and aptamer stabilized gold nanoparticles for targeted delivery of anticancer therapeutics.Aptamer TY04 inhibits the growth of multiple myeloma cells via cell cycle arrest.

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Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells.

http://www.wikidata.org/entity/Q37415807

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scientific article published on 05 August 2009

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Plasma membrane nucleolin is a ...... 1411 in MV4-11 leukemia cells.

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Plasma membrane nucleolin is a ...... 1411 in MV4-11 leukemia cells.

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Plasma membrane nucleolin is a ...... 1411 in MV4-11 leukemia cells.

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Plasma membrane nucleolin is a ...... 1411 in MV4-11 leukemia cells.

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Molecular Pharmacology

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Plasma membrane nucleolin is a ...... 1411 in MV4-11 leukemia cells.

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Daniel J Fernandes

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David Jones

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Eleanor K Spicer

http://www.w3.org/2001/XMLSchema#string

Li Wang

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Nigel Courtenay-Luck

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Sridharan Soundararajan

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Vijayalakshmi Sridharan

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Weiwei Chen

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P2860

Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA

Cloning and sequencing of the human nucleolin cDNA

The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptor

Discovery and development of anticancer aptamers

Suppression of tumor growth and angiogenesis by a specific antagonist of the cell-surface expressed nucleolin

A 110-kD nuclear shuttling protein, nucleolin, binds to the neurite-promoting IKVAV site of laminin-1

Nucleolin, the major nucleolar protein of growing eukaryotic cells: an unusual protein structure revealed by the nucleotide sequence.

Identification of nucleolin as an AU-rich element binding protein involved in bcl-2 mRNA stabilization.

Molecular dissection of nucleolin's role in growth and cell proliferation: new insights.

Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo.

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10.1124/MOL.109.055947

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19657047

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