Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77. - sprookjes - yvandenbroek - TriplyDB

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

http://www.wikidata.org/entity/Q37429232

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Orphan nuclear receptors and the regulation of nutrient metabolism: understanding obesity Nuclear receptors and epigenetic signaling: novel regulators of glycogen metabolism in skeletal muscle Interaction of ApoA-IV with NR4A1 and NR1D1 Represses G6Pase and PEPCK Transcription: Nuclear Receptor-Mediated Downregulation of Hepatic Gluconeogenesis in Mice and a Human Hepatocyte Cell Line The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK Exploring pathway interactions in insulin resistant mouse liver Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors No association between variation in the NR4A1 gene locus and metabolic traits in white subjects at increased risk for type 2 diabetes Nr4a1 is required for fasting-induced down-regulation of Pparγ2 in white adipose tissue.The nuclear receptor, Nor-1, markedly increases type II oxidative muscle fibers and resistance to fatigue.Nr4a1 siRNA expression attenuates α-MSH regulated gene expression in 3T3-L1 adipocytes Minireview: Nuclear hormone receptor 4A signaling: implications for metabolic disease.Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice.Transgenic muscle-specific Nor-1 expression regulates multiple pathways that effect adiposity, metabolism, and endurance Prostaglandin A2 enhances cellular insulin sensitivity via a mechanism that involves the orphan nuclear receptor NR4A3.NR4A orphan nuclear receptors: transcriptional regulators of gene expression in metabolism and vascular biology.Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness.NR4A1 is associated with chronic low-grade inflammation in patients with type 2 diabetes.Genetic susceptibility and loss of Nr4a1 enhances macrophage-mediated renal injury in CKD.Exercise training reverses impaired skeletal muscle metabolism induced by artificial selection for low aerobic capacity.The Drosophila NR4A nuclear receptor DHR38 regulates carbohydrate metabolism and glycogen storage.Female Nur77-deficient mice show increased susceptibility to diet-induced obesity.The orphan nuclear receptor NR4A1 specifies a distinct subpopulation of quiescent myeloid-biased long-term HSCs.Elevation of NR4A3 expression and its possible role in modulating insulin expression in the pancreatic beta cell The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice.Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function.Muscle as a "mediator" of systemic metabolism Intramuscular triacylglycerol and insulin resistance: guilty as charged or wrongly accused?Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation.Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance Nur77 deletion impairs muscle growth during developmental myogenesis and muscle regeneration in mice.Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization Cdk5r1 Overexpression Induces Primary β-Cell Proliferation.Metabolic control of the Treg/Th17 axis Nuclear receptors reverse McGarry's vicious cycle to insulin resistance.Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice Increasing muscle mass to improve metabolism.Acylcarnitines--old actors auditioning for new roles in metabolic physiology.Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing.Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes.Nur77 decreases atherosclerosis progression in apoE(-/-) mice fed a high-fat/high-cholesterol diet.

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Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

http://www.wikidata.org/entity/Q37429232

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 09 September 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

@en

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

@nl

type

label

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

@en

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

@nl

prefLabel

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

@en

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

@nl

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Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

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Andrea L Hevener

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Christopher B Newgard

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Kevin Wroblewski

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Laurent Vergnes

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Lily C Chao

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Liming Pei

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Matthew J Watt

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Olga R Ilkayeva

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Paul F Pilch

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Shi Ying Ding

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P2860

Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony

Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

Regulation of muscle fiber type and running endurance by PPARdelta

Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity

Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons

Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE

Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene

p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation

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2788-2796

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10.2337/DB09-0763

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