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Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding proteinThe anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complexQuantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulationTransducer of ERBB2.1 (TOB1) as a Tumor Suppressor: A Mechanistic PerspectiveMechanisms of deadenylation-dependent decayHeterogeneity and complexity within the nuclease module of the Ccr4-Not complexLa-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA StabilityInsights into the structure and architecture of the CCR4-NOT complexSuppression of human lung cancer cell proliferation and metastasis in vitro by the transducer of ErbB-2.1 (TOB1).Expression of B-cell translocation gene 2 is associated with favorable prognosis in hepatocellular carcinoma patients and sensitizes irradiation-induced hepatocellular carcinoma cell apoptosis in vitro and in nude miceDeadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects.Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.The iron-sensing aconitase B binds its own mRNA to prevent sRNA-induced mRNA cleavage.The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.Phosphorylation state of a Tob/BTG protein, FOG-3, regulates initiation and maintenance of the Caenorhabditis elegans sperm fate programMammalian hyperplastic discs homolog EDD regulates miRNA-mediated gene silencingEvidence providing new insights into TOB-promoted deadenylation and supporting a link between TOB's deadenylation-enhancing and antiproliferative activities.Biological role of the two overlapping poly(A)-binding protein interacting motifs 2 (PAM2) of eukaryotic releasing factor eRF3 in mRNA decay.Genomic Analyses of Sperm Fate Regulator Targets Reveal a Common Set of Oogenic mRNAs in Caenorhabditis elegansBtg2 is a Negative Regulator of Cardiomyocyte Hypertrophy through a Decrease in Cytosolic RNA.B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NFκB pathways which enhances transcription of MnSOD by accelerating IκBα degradation in normal and cancer cells.Deadenylation of cytoplasmic mRNA by the mammalian Ccr4-Not complex.Post-transcriptional regulation of DNA damage-responsive gene expressionDeadenylation: enzymes, regulation, and functional implications."The persistence of memory"-Hermaphroditism in nematodes.Expanding the repertoire of deadenylases.C. elegans FOG-3/Tob can either promote or inhibit germline proliferation, depending on gene dosage and genetic context.MicroRNA-322 (miR-322) and its target protein Tob2 modulate Osterix (Osx) mRNA stability.The interplay between transcription and mRNA degradation in Saccharomyces cerevisiaeExpression and prognosis analyses of the Tob/BTG antiproliferative (APRO) protein family in human cancers.Molecular cloning, sequence analysis, and cadmium stress-rated expression changes of BTG1 in freshwater pearl mussel (Hyriopsis schlegelii).BTG4 is a meiotic cell cycle-coupled maternal-zygotic-transition licensing factor in oocytes.The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module.Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach.BTG2 is a tumor suppressor gene upregulated by p53 and PTEN in human bladder carcinoma cells.MiR-5100 promotes osteogenic differentiation by targeting Tob2.Association between the SNPs of the TOB1 gene and gastric cancer risk in the Chinese Han population of northeast China.
P2860
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P2860
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 October 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
BTG/TOB factors impact deadenylases.
@en
BTG/TOB factors impact deadenylases.
@nl
type
label
BTG/TOB factors impact deadenylases.
@en
BTG/TOB factors impact deadenylases.
@nl
prefLabel
BTG/TOB factors impact deadenylases.
@en
BTG/TOB factors impact deadenylases.
@nl
P2093
P2860
P1476
BTG/TOB factors impact deadenylases.
@en
P2093
Ann-Bin Shyu
Chyi-Ying A Chen
Fabienne Mauxion
P2860
P304
P356
10.1016/J.TIBS.2009.07.008
P577
2009-10-12T00:00:00Z