NF-kappaB and STAT3 signaling in glioma: targets for future therapies - sprookjes - yvandenbroek - TriplyDB

NF-kappaB and STAT3 signaling in glioma: targets for future therapies

NF-kappaB and STAT3 signaling in glioma: targets for future therapies

http://www.wikidata.org/entity/Q37457873

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Radioresistance of Brain Tumors The role of NF-κB in the pathogenesis of glioma NF-κB and STAT3 in glioblastoma: therapeutic targets coming of age Curcumin inhibits neuronal and vascular degeneration in retina after ischemia and reperfusion injury JLK1486, a Bis 8-Hydroxyquinoline-Substituted Benzylamine, Displays Cytostatic Effects in Experimental Gliomas through MyT1 and STAT1 Activation and, to a Lesser Extent, PPARγ Activation Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma A novel approach to the discovery of survival biomarkers in glioblastoma using a joint analysis of DNA methylation and gene expression.Therapeutic CK2 inhibition attenuates diverse prosurvival signaling cascades and decreases cell viability in human breast cancer cells.A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors.Oncostatin-M differentially regulates mesenchymal and proneural signature genes in gliomas via STAT3 signaling.Glioma cell migration on three-dimensional nanofiber scaffolds is regulated by substrate topography and abolished by inhibition of STAT3 signaling.NF-κB and STAT3 - key players in liver inflammation and cancer The roles of endoplasmic reticulum overload response induced by HCV and NS4B protein in human hepatocyte viability and virus replication.A functional polymorphism in the pre-miR-146a gene is associated with risk and prognosis in adult glioma.Therapeutic potential of AZD1480 for the treatment of human glioblastoma Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma Heparanase induces signal transducer and activator of transcription (STAT) protein phosphorylation: preclinical and clinical significance in head and neck cancer Effect of the JAK2/STAT3 inhibitor SAR317461 on human glioblastoma tumorspheres.Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells Deletion and low expression of NFKBIA are associated with poor prognosis in lower-grade glioma patients.Activation of the NF-κB pathway by the STAT3 inhibitor JSI-124 in human glioblastoma cells.Essential role of cooperative NF-κB and Stat3 recruitment to ICAM-1 intronic consensus elements in the regulation of radiation-induced invasion and migration in glioma Activated Rac1 regulates the degradation of IκBα and the nuclear translocation of STAT3-NFκB complexes in starved cancer cells An NF-κB p65-cIAP2 link is necessary for mediating resistance to TNF-α induced cell death in gliomas NF-κB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma.Role of transcription factors in neurogenesis after cerebral ischemia.NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer.NO-Donor Iron Nitrosyl Complex with N-Ethylthiourea Ligand Exhibits Selective Toxicity to Glioma A172 Cells.Histone Deacetylase Inhibitor RGFP109 Overcomes Temozolomide Resistance by Blocking NF-κB-Dependent Transcription in Glioblastoma Cell Lines.HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies.Irradiation induces glioblastoma cell senescence and senescence-associated secretory phenotype.Icaritin Sensitizes Human Glioblastoma Cells to TRAIL-Induced Apoptosis.Synergistic Anti-Cancer Effects of Icariin and Temozolomide in Glioblastoma.SOCS3 methylation in synergy with Reg3A overexpression promotes cell growth in pancreatic cancer.Bex2 controls proliferation of human glioblastoma cells through NF-κB signaling pathway.Reverse phase protein arrays enable glioblastoma molecular subtyping.Analysis of the contribution of nasopharyngeal epithelial cancer cells to the induction of a local inflammatory response.Hepatitis C virus and its protein NS4B activate the cancer-related STAT3 pathway via the endoplasmic reticulum overload response.Effects of selenium on myocardial apoptosis by modifying the activity of mitochondrial STAT3 and regulating potassium channel expression.

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NF-kappaB and STAT3 signaling in glioma: targets for future therapies

http://www.wikidata.org/entity/Q37457873

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on April 2010

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

NF-kappaB and STAT3 signaling in glioma: targets for future therapies

@en

NF-kappaB and STAT3 signaling in glioma: targets for future therapies.

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type

label

NF-kappaB and STAT3 signaling in glioma: targets for future therapies

@en

NF-kappaB and STAT3 signaling in glioma: targets for future therapies.

@nl

prefLabel

NF-kappaB and STAT3 signaling in glioma: targets for future therapies

@en

NF-kappaB and STAT3 signaling in glioma: targets for future therapies.

@nl

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Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

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NF-kappaB and STAT3 signaling in glioma: targets for future therapies

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Etty Tika N Benveniste

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George P Atkinson

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Susan E Nozell

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P2860

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway

Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors.

Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression

Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway

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575-586

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scholarly article

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10.1586/ERN.10.21

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4

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10

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2010-04-01T00:00:00Z

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3886813

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