Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease.
about
Depletion of host CCR7(+) dendritic cells prevented donor T cell tissue tropism in anti-CD3-conditioned recipients.B7H1/CD80 interaction augments PD-1-dependent T cell apoptosis and ameliorates graft-versus-host diseaseThymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells.Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality.PD-L1 interacts with CD80 to regulate graft-versus-leukemia activity of donor CD8+ T cells.Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy.
P2860
Q33756801-A11423BA-5F52-4915-ABF6-C98649AC9E9EQ34810629-F9CD0CD0-80AC-4988-989C-F57116042E51Q37104254-23793BE3-67CE-4800-B407-A2E1513017A0Q37263177-36647BBB-DEEE-4F58-BBFB-226CA60CCFD1Q42256164-A59FC0BC-011A-41FF-B880-5F77D7F72954Q42379668-92EAEDC3-48CF-4830-8638-A7CFF29F4A0EQ49679320-4B467F90-BF1C-42E7-B38A-58B6842747A7
P2860
Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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name
Loss of B7-H1 expression by re ...... of graft-versus-host disease.
@en
Loss of B7-H1 expression by re ...... of graft-versus-host disease.
@nl
type
label
Loss of B7-H1 expression by re ...... of graft-versus-host disease.
@en
Loss of B7-H1 expression by re ...... of graft-versus-host disease.
@nl
prefLabel
Loss of B7-H1 expression by re ...... of graft-versus-host disease.
@en
Loss of B7-H1 expression by re ...... of graft-versus-host disease.
@nl
P2093
P2860
P356
P1476
Loss of B7-H1 expression by re ...... of graft-versus-host disease.
@en
P2093
Chantal Du
James Young
Lieping Chen
Paul Martin
Ruishu Deng
Stephen Forman
P2860
P304
P356
10.4049/JIMMUNOL.1102630
P407
P50
P577
2011-12-12T00:00:00Z