Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α' subunits reduces orthotopic xenograft prostate tumors in mice.
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Protein kinase CK2 and human malignant tumorsStructure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in VivoTenfibgen ligand nanoencapsulation delivers bi-functional anti-CK2 RNAi oligomer to key sites for prostate cancer targeting using human xenograft tumors in miceMechanism and efficacy of sub-50-nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma.Protein kinase CK2 inhibition induces cell death via early impact on mitochondrial function.Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle GrowthPreclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapyTenfibgen-DMAT Nanocapsule Delivers CK2 Inhibitor DMAT to Prostate Cancer Xenograft Tumors Causing Inhibition of Cell Proliferation.Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cellsGrowth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction pathways.CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors.CK2 Molecular Targeting-Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer.Casein kinase: the triple meaning of a misnomer.Protein kinase CK2 in breast cancer: the CK2β regulatory subunit takes center stage in epithelial plasticity.Therapeutic Targeting of Protein Kinase CK2 Gene Expression in Feline Oral Squamous Cell Carcinoma: A Naturally Occurring Large-Animal Model of Head and Neck Cancer.Examination of CK2α and NF-κB p65 expression in human benign prostatic hyperplasia and prostate cancer tissues.Taxifolin, a natural flavonoid interacts with cell cycle regulators causes cell cycle arrest and causes tumor regression by activating Wnt/ β -catenin signaling pathway
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Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α' subunits reduces orthotopic xenograft prostate tumors in mice.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 July 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Systemic administration of ant ...... graft prostate tumors in mice.
@en
Systemic administration of ant ...... graft prostate tumors in mice.
@nl
type
label
Systemic administration of ant ...... graft prostate tumors in mice.
@en
Systemic administration of ant ...... graft prostate tumors in mice.
@nl
prefLabel
Systemic administration of ant ...... graft prostate tumors in mice.
@en
Systemic administration of ant ...... graft prostate tumors in mice.
@nl
P2093
P2860
P1476
Systemic administration of ant ...... graft prostate tumors in mice.
@en
P2093
Betsy T Kren
Diane K Tobolt
Gretchen M Unger
Guixia Wang
Janeen H Trembley
Joel W Slaton
Kashif A Ahmad
Khalil Ahmed
Vicci L Korman
P2860
P2888
P356
10.1007/S11010-011-0943-X
P577
2011-07-15T00:00:00Z