Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
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1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal StructureAPOBEC3 Interference during Replication of Viral GenomesA DNA sequence recognition loop on APOBEC3A controls substrate specificityTransient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes.Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization.Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities.Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA.APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophagesDNA cytosine and methylcytosine deamination by APOBEC3B: enhancing methylcytosine deamination by engineering APOBEC3B.Molecular basis of the attenuated phenotype of human APOBEC3B DNA mutator enzyme.Integrative genomic analysis reveals functional diversification of APOBEC gene family in breast cancer.The ssDNA Mutator APOBEC3A Is Regulated by Cooperative DimerizationAPOBEC3A damages the cellular genome during DNA replicationSingle-Molecule Force Spectroscopy Studies of APOBEC3A-Single-Stranded DNA Complexes.Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity.Crystal structures of APOBEC3G N-domain alone and its complex with DNA.Differential inhibition of LINE1 and LINE2 retrotransposition by vertebrate AID/APOBEC proteins.Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.Structural and functional assessment of APOBEC3G macromolecular complexes.Cellular HIV-1 inhibition by truncated old world primate APOBEC3A proteins lacking a complete deaminase domain.Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression.The in vitro Biochemical Characterization of an HIV-1 Restriction Factor APOBEC3F: Importance of Loop 7 on Both CD1 and CD2 for DNA Binding and Deamination.Influence of the DNA sequence/length and pH on deaminase activity, as well as the roles of the amino acid residues around the catalytic center of APOBEC3F.Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA.Computational Model and Dynamics of Monomeric Full-Length APOBEC3G.Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B.Stem-loop structure preference for site-specific RNA editing by APOBEC3A and APOBEC3G.Mechanisms for targeted, purposeful mutation revealed in an APOBEC-DNA complex.Asymmetric Modification of Hepatitis B Virus (HBV) Genomes by an Endogenous Cytidine Deaminase inside HBV Cores Informs a Model of Reverse Transcription.Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions.Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid LigandsAPOBEC3B Activity Is Prevalent in Urothelial Carcinoma Cells and Only Slightly Affected by LINE-1 Expression
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Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
@en
Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
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type
label
Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
@en
Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
@nl
prefLabel
Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
@en
Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
@nl
P2093
P2860
P356
P1476
Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
@en
P2093
Chang-Hyeock Byeon
Dustin Singer
Gabriel Nam
Gisela Heidecker
In-Ja L Byeon
Jinwoo Ahn
Judith G Levin
Kamil Hercík
Kathyrn Hinchee-Rodriguez
Lisa M Charlton
P2860
P304
P356
10.1093/NAR/GKT945
P407
P577
2013-10-24T00:00:00Z