about
Dynamics of chromatin accessibility during TGF-β-induced EMT of Ras-transformed mammary gland epithelial cells.Whole-Genome Sequence of the Metastatic PC3 and LNCaP Human Prostate Cancer Cell Lines.Comparative transcriptome analysis of isogenic cell line models and primary cancers links capicua (CIC) loss to activation of the MAPK signalling cascadeGeneration of novel patient-derived CIC- DUX4 sarcoma xenografts and cell lines.Cofilin 1 induces the epithelial-mesenchymal transition of gastric cancer cells by promoting cytoskeletal rearrangement.A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer.Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5.miR-551b regulates epithelial-mesenchymal transition and metastasis of gastric cancer by inhibiting ERBB4 expression.CIC break-apart fluorescence in-situ hybridization misses a subset of CIC-DUX4 sarcomas: a clinicopathological and molecular study.Parallel imaging of Drosophila embryos for quantitative analysis of genetic perturbations of the Ras pathway.ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition.COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation.Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers.Metastasis: From head to tail.A double-edged sword: The world according to Capicua in cancer.ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1.Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma.Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.The COP9 signalosome inhibits Cullin-RING E3 ubiquitin ligases independently of its deneddylase activity.Capicua controls Toll/IL-1 signaling targets independently of RTK regulation.Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication.The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer.The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation
P2860
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P2860
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Inactivation of Capicua drives cancer metastasis
@en
Inactivation of Capicua drives cancer metastasis.
@nl
type
label
Inactivation of Capicua drives cancer metastasis
@en
Inactivation of Capicua drives cancer metastasis.
@nl
prefLabel
Inactivation of Capicua drives cancer metastasis
@en
Inactivation of Capicua drives cancer metastasis.
@nl
P2093
P2860
P356
P1433
P1476
Inactivation of Capicua drives cancer metastasis
@en
P2093
Andrew D Simmons
Asmin Tulpule
Beatrice Gini
Collin M Blakely
Frank Breitenbuecher
Gorjan Hrustanovic
Henry J Haringsma
Jennifer Flanagan
Kyle Gowen
P2860
P2888
P356
10.1038/NG.3728
P407
P577
2016-11-21T00:00:00Z