New natural product biosynthetic chemistry discovered by genome mining.
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Mining of the pyrrolamide antibiotics analogs in Streptomyces netropsis reveals the amidohydrolase-dependent "iterative strategy" underlying the pyrrole polymerizationEndless Resistance. Endless Antibiotics?Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilolCurrent approaches to exploit actinomycetes as a source of novel natural products.Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?Synthesis of a bicyclobutane fatty acid identified from the cyanobacterium Anabaena PCC 7120Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains.Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived Aspergillus spThe impact of plant-pathogen studies on medicinal drug discovery.Genome mining in Streptomyces clavuligerus: expression and biochemical characterization of two new cryptic sesquiterpene synthases.Draft genome sequence of the marine sediment-derived actinomycete Streptomyces xinghaiensis NRRL B24674T.Transcriptome mining of active biosynthetic pathways and their associated products in Streptomyces flaveolus.Frenolicins C-G, pyranonaphthoquinones from Streptomyces sp. RM-4-15The marine actinomycete genus Salinispora: a model organism for secondary metabolite discoveryDereplicating nonribosomal peptides using an informatic search algorithm for natural products (iSNAP) discovery.A sea of biosynthesis: marine natural products meet the molecular age.Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities.A Genomic, Transcriptomic and Proteomic Look at the GE2270 Producer Planobispora rosea, an Uncommon ActinomyceteSystematic unravelling of the biosynthesis of poly (L-diaminopropionic acid) in Streptomyces albulus PD-1.Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria.Metabolic profiling as a tool for prioritizing antimicrobial compoundsIdentification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome MiningScreening for Expressed Nonribosomal Peptide Synthetases and Polyketide Synthases Using LC-MS/MS-Based Proteomics.MS/MS networking guided analysis of molecule and gene cluster families.Constructing de novo biosynthetic pathways for chemical synthesis inside living cells.Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules.Genome-guided discovery of diverse natural products from Burkholderia sp.Epigenome manipulation as a pathway to new natural product scaffolds and their congeners.Prenylated indole derivatives from fungi: structure diversity, biological activities, biosynthesis and chemoenzymatic synthesis.Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora.Ergot alkaloids: structure diversity, biosynthetic gene clusters and functional proof of biosynthetic genes.Strain improvement in actinomycetes in the postgenomic era.The regulation of the secondary metabolism of Streptomyces: new links and experimental advances.Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery.Exploration and mining of the bacterial terpenome.Microalgae in the postgenomic era: a blooming reservoir for new natural products.Ribosome-independent biosynthesis of biologically active peptides: Application of synthetic biology to generate structural diversity.The application of Chinese medicine to novel drug discovery.Discovering new bioactive molecules from microbial sources.Thinking big about small beings--the (yet) underdeveloped microbial natural products chemistry in Brazil.
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P2860
New natural product biosynthetic chemistry discovered by genome mining.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 22 May 2009
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vedecký článok
@sk
vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
New natural product biosynthetic chemistry discovered by genome mining.
@en
New natural product biosynthetic chemistry discovered by genome mining.
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type
label
New natural product biosynthetic chemistry discovered by genome mining.
@en
New natural product biosynthetic chemistry discovered by genome mining.
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prefLabel
New natural product biosynthetic chemistry discovered by genome mining.
@en
New natural product biosynthetic chemistry discovered by genome mining.
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P356
P1476
New natural product biosynthetic chemistry discovered by genome mining.
@en
P304
P356
10.1039/B713024B
P577
2009-05-22T00:00:00Z