G1 arrest and down-regulation of cyclin E/cyclin-dependent kinase 2 by the protein kinase inhibitor staurosporine are dependent on the retinoblastoma protein in the bladder carcinoma cell line 5637.
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Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2Cigarette smoke triggers code red: p21CIP1/WAF1/SDI1 switches on danger responses in the lung.Staurosporine is chemoprotective by inducing G1 arrest in a Chk1- and pRb-dependent mannerCyclin dependent protein kinases and stress responses in plants.Combination of Zizyphus jujuba and green tea extracts exerts excellent cytotoxic activity in HepG2 cells via reducing the expression of APRIL.Green tea extract enhances the selective cytotoxic activity of Zizyphus jujuba extracts in HepG2 cells.RB activity alters checkpoint response and chemosensitivity in lung cancer lines.Staurosporine modulates radiosensitivity and radiation-induced apoptosis in U937 cells.Screening of five specific cell cycle inhibitors using a T cell lymphoma cell line synchrony/release assay.Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells.Identification of cytosolic aldehyde dehydrogenase 1 from non-small cell lung carcinomas as a flavopiridol-binding protein.Growth inhibition by the muscarinic M(3) acetylcholine receptor: evidence for p21(Cip1/Waf1) involvement in G(1) arrest.Phosphorylation site mutated RB exerts contrasting effects on apoptotic response to different stimuli.
P2860
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P2860
G1 arrest and down-regulation of cyclin E/cyclin-dependent kinase 2 by the protein kinase inhibitor staurosporine are dependent on the retinoblastoma protein in the bladder carcinoma cell line 5637.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 1996
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
G1 arrest and down-regulation ...... dder carcinoma cell line 5637.
@en
G1 arrest and down-regulation ...... dder carcinoma cell line 5637.
@nl
type
label
G1 arrest and down-regulation ...... dder carcinoma cell line 5637.
@en
G1 arrest and down-regulation ...... dder carcinoma cell line 5637.
@nl
prefLabel
G1 arrest and down-regulation ...... dder carcinoma cell line 5637.
@en
G1 arrest and down-regulation ...... dder carcinoma cell line 5637.
@nl
P2093
P2860
P356
P1476
G1 arrest and down-regulation ...... dder carcinoma cell line 5637.
@en
P2093
D W Goodrich
E M Bradbury
J B Schnier
P2860
P304
P356
10.1073/PNAS.93.12.5941
P407
P577
1996-06-01T00:00:00Z