Repression of human T-cell leukemia virus type 1 and type 2 replication by a viral mRNA-encoded posttranscriptional regulator.
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Mouse mammary tumor virus encodes a self-regulatory RNA export protein and is a complex retrovirus.HTLV-1 p30II: selective repressor of gene expressionHuman T lymphotropic virus type-1 p30II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytesThe need to accessorize: molecular roles of HTLV-1 p30 and HTLV-2 p28 accessory proteins in the viral life cycleA human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactionsGenome wide analysis of human genes transcriptionally and post-transcriptionally regulated by the HTLV-I protein p30.Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13II sensitizes Jurkat T cells to Ras-mediated apoptosisHuman T-cell leukemia virus type 1 expressing nonoverlapping tax and rex genes replicates and immortalizes primary human T lymphocytes but fails to replicate and persist in vivo.Human T-cell leukemia virus open reading frame II encodes a posttranscriptional repressor that is recruited at the level of transcription.Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13(II) is required for viral infectivity in vivo.Histone acetyltransferase (HAT) activity of p300 modulates human T lymphotropic virus type 1 p30II-mediated repression of LTR transcriptional activity.Human T-lymphotropic virus type 1 p30 interacts with REGgamma and modulates ATM (ataxia telangiectasia mutated) to promote cell survival.The human T-cell leukemia virus type 1 p13II protein: effects on mitochondrial function and cell growthDiscovery and characterization of auxiliary proteins encoded by type 3 simian T-cell lymphotropic virusesAcetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC.Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis.Orf-I and orf-II-encoded proteins in HTLV-1 infection and persistence.Molecular determinants of human T-lymphotropic virus type 1 transmission and spread.Converging strategies in expression of human complex retrovirusesA reduction of viral mRNA, proteins and induction of altered morphogenesis reveals the anti-HTLV-1 activity of the labdane-diterpene myriadenolide in vitro.Selective repression of translation by the brome mosaic virus 1a RNA replication protein.Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1.Human T lymphotropic virus type 1 regulatory and accessory gene transcript expression and export are not rex dependent.Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival.Detection and quantitation of HTLV-1 and HTLV-2 mRNA species by real-time RT-PCR.Human T-cell leukemia virus type 2 antisense viral protein 2 is dispensable for in vitro immortalization but functions to repress early virus replication in vivo.Animal models for human T-lymphotropic virus type 1 (HTLV-1) infection and transformation.Human T-cell leukemia/lymphoma virus type 1 nonstructural genes and their functions.Comparative host protein interactions with HTLV-1 p30 and HTLV-2 p28: insights into difference in pathobiology of human retroviruses.Expression of Alternatively Spliced Human T-Cell Leukemia Virus Type 1 mRNAs Is Influenced by Mitosis and by a Novel cis-Acting Regulatory Sequence.PRMT5 Is Upregulated in HTLV-1-Mediated T-Cell Transformation and Selective Inhibition Alters Viral Gene Expression and Infected Cell Survival.PA28γ is a novel corepressor of HTLV-1 replication and controls viral latency.Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo.Functional Comparison of HBZ and the Related APH-2 Protein Provides Insight into Human T-Cell Leukemia Virus Type 1 Pathogenesis.Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation.Molecular aspects of HTLV-I infection and adult T-cell leukaemia/lymphoma.Kinetic analysis of human T-cell leukemia virus type 1 gene expression in cell culture and infected animalsHTLV-1 Yin and Yang: Rex and p30 master regulators of viral mRNA trafficking.HTLV gene regulation: because size matters, transcription is not enough.Discovery and significance of new human T-lymphotropic viruses: HTLV-3 and HTLV-4.
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P2860
Repression of human T-cell leukemia virus type 1 and type 2 replication by a viral mRNA-encoded posttranscriptional regulator.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Repression of human T-cell leu ...... posttranscriptional regulator.
@en
Repression of human T-cell leu ...... posttranscriptional regulator.
@nl
type
label
Repression of human T-cell leu ...... posttranscriptional regulator.
@en
Repression of human T-cell leu ...... posttranscriptional regulator.
@nl
prefLabel
Repression of human T-cell leu ...... posttranscriptional regulator.
@en
Repression of human T-cell leu ...... posttranscriptional regulator.
@nl
P2093
P2860
P1433
P1476
Repression of human T-cell leu ...... posttranscriptional regulator.
@en
P2093
Genoveffa Franchini
Ihab Younis
Lyne Khair
Michael D Lairmore
Miroslav Dundr
Patrick L Green
P2860
P304
11077-11083
P356
10.1128/JVI.78.20.11077-11083.2004
P407
P577
2004-10-01T00:00:00Z