The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt.
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Arachidonic acid monooxygenase: Genetic and biochemical approaches to physiological/pathophysiological relevanceCytochrome P450 eicosanoids in hypertension and renal diseaseEpoxyeicosatrienoic acids, hypertension, and kidney injuryAssociation of gain-of-function EPHX2 polymorphism Lys55Arg with acute kidney injury following cardiac surgeryCharacterization of the Tissue Distribution of the Mouse Cyp2c Subfamily by Quantitative PCR Analysis.Epoxyeicosatrienoic Acid Analog Decreases Renal Fibrosis by Reducing Epithelial-to-Mesenchymal Transition.Epoxyeicosatrienoic Acids and 20-Hydroxyeicosatetraenoic Acid on Endothelial and Vascular Function.Cyp2c44 epoxygenase in the collecting duct is essential for the high K+ intake-induced antihypertensive effect.Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.Overexpression of G-protein-coupled receptor 40 enhances the mitogenic response to epoxyeicosatrienoic acidsCyp2c44 gene disruption exacerbated pulmonary hypertension and heart failure in female but not male miceCytochrome P450 and Lipoxygenase Metabolites on Renal Function.Effect of Cytochrome P450 Metabolites of Arachidonic Acid in Nephrology.20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: NORMALIZATION OF BLOOD PRESSURE BY SODIUM RESTRICTION, HYDROCHLOROTHIAZIDE, OR BLOCKADE OF THE TYPE 1 ANGIOTENSIN II RECEPTOR.Two Pools of Epoxyeicosatrienoic Acids in Humans: Alterations in Salt-Sensitive Normotensive Subjects.Cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids contribute to insulin sensitivity in mice and in humans.Orally Active Epoxyeicosatrienoic Acid Analogs.Cyp2c44 gene disruption is associated with increased hematopoietic stem cells: implication in chronic hypoxia-induced pulmonary hypertension.
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The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The Cyp2c44 epoxygenase regula ...... ses to increased dietary salt.
@en
The Cyp2c44 epoxygenase regula ...... ses to increased dietary salt.
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type
label
The Cyp2c44 epoxygenase regula ...... ses to increased dietary salt.
@en
The Cyp2c44 epoxygenase regula ...... ses to increased dietary salt.
@nl
prefLabel
The Cyp2c44 epoxygenase regula ...... ses to increased dietary salt.
@en
The Cyp2c44 epoxygenase regula ...... ses to increased dietary salt.
@nl
P2093
P2860
P356
P1476
The Cyp2c44 epoxygenase regula ...... nses to increased dietary salt
@en
P2093
John R Falck
Jorge H Capdevila
Nataliya Pidkovka
Raymond C Harris
Shaojun Mei
Wenhui Wang
P2860
P304
P356
10.1074/JBC.M113.508416
P407
P50
P577
2013-12-24T00:00:00Z