Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.

Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.

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http://www.wikidata.org/entity/Q37591245
A simple mathematical approach to the analysis of polypharmacology and polyspecificity data.Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions.Targeted delivery of ginsenoside compound K using TPGS/PEG-PCL mixed micelles for effective treatment of lung cancer.Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency.The reliability of molecular dynamics simulations of the multidrug transporter P-glycoprotein in a membrane environment.Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.Coarse-grained molecular dynamics simulations reveal lipid access pathways in P-glycoprotein.Conformational dynamics of P-glycoprotein in lipid nanodiscs and detergent micelles reveal complex motions on a wide time scale.Vasohibin 1 inhibits Adriamycin resistance in osteosarcoma cells via the protein kinase B signaling pathway.Dissecting the Forces that Dominate Dimerization of the Nucleotide Binding Domains of ABCB1.Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoproteinOvercoming P-Glycoprotein-Mediated Multidrug Resistance in Colorectal Cancer: Potential Reversal Agents among Herbal MedicinesATP-binding cassette transporters in progression and clinical outcome of pancreatic cancer: What is the way forward?Evidence for the critical role of transmembrane helices 1 and 7 in substrate transport by human P-glycoprotein (ABCB1)
P2860

Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.

Item
http://www.wikidata.org/entity/Q37591245
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Structures of the Multidrug Tr ...... Mechanism of Polyspecificity.
@en
Structures of the Multidrug Tr ...... Mechanism of Polyspecificity.
@nl
type
label
Structures of the Multidrug Tr ...... Mechanism of Polyspecificity.
@en
Structures of the Multidrug Tr ...... Mechanism of Polyspecificity.
@nl
prefLabel
Structures of the Multidrug Tr ...... Mechanism of Polyspecificity.
@en
Structures of the Multidrug Tr ...... Mechanism of Polyspecificity.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Structures of the Multidrug Tr ...... Mechanism of Polyspecificity.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932