Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer. - sprookjes - yvandenbroek - TriplyDB

Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer.

Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer.

http://www.wikidata.org/entity/Q37622949

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Chronic Cigarette Smoke Mediated Global Changes in Lung Mucoepidermoid Cells: A Phosphoproteomic Analysis.MUC1-C activates polycomb repressive complexes and downregulates tumor suppressor genes in human cancer cells.Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: A report of two instructive cases.

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Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer.

http://www.wikidata.org/entity/Q37622949

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scientific article published on 02 February 2017

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Targeting MUC1-C inhibits the ...... nslation in colorectal cancer.

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Targeting MUC1-C inhibits the ...... nslation in colorectal cancer.

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Targeting MUC1-C inhibits the ...... nslation in colorectal cancer.

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S12943-017-0608-9

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Molecular Cancer

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Targeting MUC1-C inhibits the ...... nslation in colorectal cancer.

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Donald Kufe

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Maroof Alam

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Masanori Hasegawa

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Omar Al-Obaid

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Rehan Ahmad

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Surender Kharbanda

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Yasumitsu Uchida

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P2860

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Inhibition of the MUC1-C oncoprotein induces multiple myeloma cell death by down-regulating TIGAR expression and depleting NADPH

Comprehensive molecular characterization of human colon and rectal cancer

MUC1 and colorectal cancer pathophysiology considerations

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion

S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90

MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin

TIGAR is required for efficient intestinal regeneration and tumorigenesis

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colorectal cancer

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