Lats2 is critical for the pluripotency and proper differentiation of stem cells. - sprookjes - yvandenbroek - TriplyDB

Lats2 is critical for the pluripotency and proper differentiation of stem cells.

Lats2 is critical for the pluripotency and proper differentiation of stem cells.

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Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.The Hippo pathway in tissue homeostasis and regeneration.LATS2 Positively Regulates Polycomb Repressive Complex 2.Down-regulation of LATS kinases alters p53 to promote cell migration.The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation Human pluripotent stem cell culture density modulates YAP signaling The Hippo pathway, p53 and cholesterol The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathway.p53 shades of Hippo.Hippo signaling controls cell cycle and restricts cell plasticity in planarians.

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Lats2 is critical for the pluripotency and proper differentiation of stem cells.

http://www.wikidata.org/entity/Q37631183

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 10 January 2014

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Lats2 is critical for the pluripotency and proper differentiation of stem cells.

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Lats2 is critical for the pluripotency and proper differentiation of stem cells.

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type

label

Lats2 is critical for the pluripotency and proper differentiation of stem cells.

@en

Lats2 is critical for the pluripotency and proper differentiation of stem cells.

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prefLabel

Lats2 is critical for the pluripotency and proper differentiation of stem cells.

@en

Lats2 is critical for the pluripotency and proper differentiation of stem cells.

@nl

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Cell Death & Differentiation

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Lats2 is critical for the pluripotency and proper differentiation of stem cells.

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P2860

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

The hippo signaling pathway in development and cancer

Tumor suppressors: enhancers or suppressors of regeneration?

A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction

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624-633

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scholarly article

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10.1038/CDD.2013.188

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