Alternative splicing: regulation of HIV-1 multiplication as a target for therapeutic action.
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Translational Control of the HIV Unspliced Genomic RNADigoxin suppresses HIV-1 replication by altering viral RNA processingLong lasting control of viral rebound with a new drug ABX464 targeting Rev - mediated viral RNA biogenesis.Functional bottlenecks for generation of HIV-1 intersubtype Env recombinants.Argonaute proteins regulate HIV-1 multiply spliced RNA and viral production in a Dicer independent mannerExpression of Herpes Simplex Virus Thymidine Kinase/Ganciclovir by RNA Trans-Splicing Induces Selective Killing of HIV-Producing Cells.Safety, Pharmacokinetics, and Antiviral Activity of a Novel HIV Antiviral, ABX464, in Treatment-Naive HIV-Infected Subjects in a Phase 2 Randomized, Controlled StudyAlternative splicing regulated by butyrate in bovine epithelial cells.Models for predicting effective HIV chemoprevention in womenDifferential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy.Converging strategies in expression of human complex retrovirusesIsolation of a TRAIL antagonist from the serum of HIV-infected patients.Pharmacodynamic assays to facilitate preclinical and clinical development of pre-mRNA splicing modulatory drug candidates.Human Papillomavirus E2 Protein: Linking Replication, Transcription, and RNA Processing.Characterization of novel inhibitors of HIV-1 replication that function via alteration of viral RNA processing and rev functionHIV-1 Vpr N-terminal tagging affects alternative splicing of the viral genome.Randomized Trial of Food Effect on Pharmacokinetic Parameters of ABX464 Administered Orally to Healthy Male Subjects.Natural single-nucleotide polymorphisms in the 3' region of the HIV-1 pol gene modulate viral replication ability.Enhancing protein backbone binding--a fruitful concept for combating drug-resistant HIV.Putting an 'End' to HIV mRNAs: capping and polyadenylation as potential therapeutic targets.Influenza viruses and mRNA splicing: doing more with lessA multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA.Can the HIV-1 splicing machinery be targeted for drug discovery?Embryonic expression of endogenous retroviral RNAs in somatic tissues adjacent to the Oikopleura germlineEnhanced SRSF5 Protein Expression Reinforces Lamin A mRNA Production in HeLa Cells and Fibroblasts of Progeria Patients.Pharmacokinetics and tolerability of ABX464, a novel first-in-class compound to treat HIV infection, in healthy HIV-uninfected subjects.Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication.Stably integrated and expressed retroviral sequences can influence nuclear location and chromatin condensation of the integration locus.Nuclear speckles: molecular organization, biological function and role in disease.Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication.Splicing of HIV RNA transcriptSynthesis of VPU proteinIdiosyncrasies of hnRNP A1-RNA recognition: Can binding mode influence function.Splicing Factor 3B Subunit 1 Interacts with HIV Tat and Plays a Role in Viral Transcription and Reactivation from LatencyDDX17 Specifically, and Independently of DDX5, Controls Use of the HIV A4/5 Splice Acceptor Cluster and Is Essential for Efficient Replication of HIV
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Alternative splicing: regulation of HIV-1 multiplication as a target for therapeutic action.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 January 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Alternative splicing: regulati ...... target for therapeutic action.
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Alternative splicing: regulati ...... target for therapeutic action.
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type
label
Alternative splicing: regulati ...... target for therapeutic action.
@en
Alternative splicing: regulati ...... target for therapeutic action.
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prefLabel
Alternative splicing: regulati ...... target for therapeutic action.
@en
Alternative splicing: regulati ...... target for therapeutic action.
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Alternative splicing: regulati ...... target for therapeutic action.
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Amina Aboufirassi
Christiane Branlant
Lilia Ayadi
Nadia Bakkour
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P304
P356
10.1111/J.1742-4658.2009.07522.X
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P577
2010-01-15T00:00:00Z