Patented inhibitors of p53-Mdm2 interaction (2006 - 2008).
about
miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stressChemical Variations on the p53 Reactivation ThemeThe structure of an MDM2-Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutantOverexpression of the catalytically impaired Taspase1 T234V or Taspase1 D233A variants does not have a dominant negative effect in T(4;11) leukemia cellsSwimming into peptidomimetic chemical space using pepMMsMIMIC.MDM2 SNP309 promoter polymorphism and p53 mutations in urinary bladder carcinoma stage T1.Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach.Small-molecule MDM2-p53 inhibitors: recent advances.Identification of FDA-approved drugs that computationally bind to MDM2The p53-MDM2/MDMX axis - A chemotype perspective.The structure-based design of Mdm2/Mdmx-p53 inhibitors gets seriousMdm2 and MdmX inhibitors for the treatment of cancer: a patent review (2011-present).Resistance acquisition to MDM2 inhibitors.Targeting p53-MDM2-MDMX loop for cancer therapy.2-Indolinone a versatile scaffold for treatment of cancer: a patent review (2008-2014).Synthesis of spiro[isoindole-1,5'-isoxazolidin]-3(2H)-ones as potential inhibitors of the MDM2-p53 interaction.Spiro-oxindoles as a Promising Class of Small Molecule Inhibitors of p53-MDM2 Interaction Useful in Targeted Cancer Therapy.
P2860
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P2860
Patented inhibitors of p53-Mdm2 interaction (2006 - 2008).
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on February 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Patented inhibitors of p53-Mdm2 interaction (2006 - 2008).
@en
Patented inhibitors of p53-Mdm2 interaction
@nl
type
label
Patented inhibitors of p53-Mdm2 interaction (2006 - 2008).
@en
Patented inhibitors of p53-Mdm2 interaction
@nl
prefLabel
Patented inhibitors of p53-Mdm2 interaction (2006 - 2008).
@en
Patented inhibitors of p53-Mdm2 interaction
@nl
P2860
P1476
Patented inhibitors of p53-Mdm2 interaction (2006 - 2008).
@en
P2093
Lutz Weber
P2860
P304
P356
10.1517/13543770903514129
P407
P577
2010-02-01T00:00:00Z