Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells.
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Emodin and rhein decrease levels of hypoxia-inducible factor-1α in human pancreatic cancer cells and attenuate cancer cachexia in athymic mice carrying these cells.Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL.Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer.Small interfering RNA-mediated knockdown of fatty acid synthase attenuates the proliferation and metastasis of human gastric cancer cells via the mTOR/Gli1 signaling pathway.
P2860
Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 January 2017
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Multi-level suppression of rec ...... against ovarian cancer cells.
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Multi-level suppression of rec ...... against ovarian cancer cells.
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type
label
Multi-level suppression of rec ...... against ovarian cancer cells.
@en
Multi-level suppression of rec ...... against ovarian cancer cells.
@nl
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Multi-level suppression of rec ...... against ovarian cancer cells.
@en
Multi-level suppression of rec ...... against ovarian cancer cells.
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P2093
P2860
P50
P356
P1433
P1476
Multi-level suppression of rec ...... against ovarian cancer cells.
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P2093
Christian F Singer
Daniel Veigel
Emmanouil Karteris
Gerald Stübiger
Julian Weghuber
Karin Nowikovsky
Michael Wuczkowski
Nastasia Wilfinger-Lutz
Renate Wagner
Thomas W Grunt
P2860
P304
11600-11613
P356
10.18632/ONCOTARGET.14591
P407
P577
2017-01-10T00:00:00Z