Site-specific mutagenesis: retrospective and prospective.
about
Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanineA 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatchPharmacogenetics: detecting sensitive populationsRepair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases.The endogenous exposome.A bifunctional DNA repair protein from Ferroplasma acidarmanus exhibits O6-alkylguanine-DNA alkyltransferase and endonuclease V activities.Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein.Quantitation of 7-ethylguanine in leukocyte DNA from smokers and nonsmokers by liquid chromatography-nanoelectrospray-high resolution tandem mass spectrometry.A new LC-MS/MS method for the quantification of endogenous and vinyl chloride-induced 7-(2-Oxoethyl)guanine in sprague-dawley rats.Mutagenesis by O6 meG residues within codon 12 of the human Ha-ras proto-oncogene in monkey cells.Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells.The frequency and accuracy of replication past a thymine-thymine cyclobutane dimer are very different in Saccharomyces cerevisiae and Escherichia coli.Vinyl chloride-a classical industrial toxicant of new interest.Evidence from in vitro replication that O6-methylguanine can adopt multiple conformationsIn-vitro replication studies on O(2)-methylthymidine and O(4)-methylthymidineAn intercalation inhibitor altering the target selectivity of DNA damaging agents: synthesis of site-specific aflatoxin B1 adducts in a p53 mutational hotspot.Progress and challenges in selected areas of tobacco carcinogenesisRelationship between O6-alkylguanine-DNA alkyltransferase activity and N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation, transformation, and cytotoxicity in C3H/10T1/2 cells expressing exogenous alkyltransferase genes.Screening for DNA Alkylation Mono and Cross-Linked Adducts with a Comprehensive LC-MS(3) Adductomic ApproachThe vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli.In vivo and in vitro replication consequences of stereoisomeric benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide adducts on adenine N6 at the second position of N-ras codon 61.DNA polymerase II (polB) is involved in a new DNA repair pathway for DNA interstrand cross-links in Escherichia coliDevelopment and use of an in vitro HSV-tk forward mutation assay to study eukaryotic DNA polymerase processing of DNA alkyl lesions.Site-specific mutagenesis induced by single O6-alkylguanines (O6-n-propyl, O6-n-butyl, O6-n-octyl) in vivo.Alkylation damage repair protein O6-alkylguanine-DNA alkyltransferase from the hyperthermophiles Aquifex aeolicus and Archaeoglobus fulgidus.
P2860
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P2860
Site-specific mutagenesis: retrospective and prospective.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Site-specific mutagenesis: retrospective and prospective.
@en
Site-specific mutagenesis: retrospective and prospective.
@nl
type
label
Site-specific mutagenesis: retrospective and prospective.
@en
Site-specific mutagenesis: retrospective and prospective.
@nl
prefLabel
Site-specific mutagenesis: retrospective and prospective.
@en
Site-specific mutagenesis: retrospective and prospective.
@nl
P356
P1433
P1476
Site-specific mutagenesis: retrospective and prospective.
@en
P2093
Essigmann JM
P304
P356
10.1093/CARCIN/12.6.949
P407
P577
1991-06-01T00:00:00Z