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A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cellsA new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging[Ca2+]i as a potential downregulator of alpha2beta1-integrin-mediated A2058 tumor cell migration to type IV collagenSpatial regulation of RhoC activity defines protrusion formation in migrating cellsSpatiotemporal dynamics of RhoA activity in migrating cellsMacrophage contact induces RhoA GTPase signaling to trigger tumor cell intravasation.A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior.Synonymous modification results in high-fidelity gene expression of repetitive protein and nucleotide sequences.Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions.Correcting mitochondrial fusion by manipulating mitofusin conformations.Functional proteometrics for cell migration.Digital autofocus methods for automated microscopy.A biosensor of S100A4 metastasis factor activation: inhibitor screening and cellular activation dynamics.Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis.Extracellular lipid-mediated signaling in tumor-cell activation and pseudopod protrusion.Induction of entosis by epithelial cadherin expressionIntracellular calcium changes in rat aortic smooth muscle cells in response to fluid flow.Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes.Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation.Dynamics of the Rho-family small GTPases in actin regulation and motility.Directed cell invasion and migration during metastasis.Functions of cofilin in cell locomotion and invasion.Spatial regulation of tumor cell protrusions by RhoC.Rho GTPase isoforms in cell motility: Don't fret, we have FRET.A mix-and-measure assay for determining the activation status of endogenous Cdc42 in cytokine-stimulated macrophage cell lysates.Live cell imaging of RhoGTPase biosensors in tumor cells.Digital differential interference contrast autofocus for high-resolution oil-immersion microscopy.Multiplex imaging of Rho family GTPase activities in living cells.Use of green fluorescent protein-conjugated beta-actin as a novel molecular marker for in vitro tumor cell chemotaxis assayDesign and optimization of genetically encoded fluorescent biosensors: GTPase biosensors.Combining surface chemistry with a FRET-based biosensor to study the dynamics of RhoA GTPase activation in cells on patterned substrates.Biosensors for characterizing the dynamics of rho family GTPases in living cells.The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis.Melanoma cell migration to type IV collagen requires activation of NF-kappaBControl of mitochondrial function and cell growth by the atypical cadherin Fat1.Quantitative ratiometric imaging of FRET-biosensors in living cells.Involvement of phospholipase C signaling in melanoma cell-induced endothelial junction disassembly.A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia.
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Louis Hodgson
@ast
Louis Hodgson
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Louis Hodgson
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Louis Hodgson
@nl
Louis Hodgson
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لويس هودسون
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type
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Louis Hodgson
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Louis Hodgson
@en
Louis Hodgson
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Louis Hodgson
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Louis Hodgson
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لويس هودسون
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Hodgson L
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Louis Hodgson
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Louis Hodgson
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Louis Hodgson
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Louis Hodgson
@nl
Louis Hodgson
@sl
لويس هودسون
@ar
P106
P21
P31
P496
0000-0001-9188-7580