5-Fluorouracil pharmacogenomics: still rocking after all these years?
about
Evaluating predictive pharmacogenetic signatures of adverse events in colorectal cancer patients treated with fluoropyrimidinesPharmacogenetics research on chemotherapy resistance in colorectal cancer over the last 20 yearsDihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity.Targeting a regulatory element in human thymidylate synthase mRNA.Polymorphisms in folate-metabolizing enzymes and response to 5-fluorouracil among patients with stage II or III rectal cancer (INT-0144; SWOG 9304).Locally advanced rectal cancer: the importance of a multidisciplinary approach.Analysis of mRNA recognition by human thymidylate synthase.5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-β-synthase in colon cancer cells lacking p53.In vivo 5FU-exposed human medullary thyroid carcinoma cells contain a chemoresistant CD133+ tumor-initiating cell subsetOperable gastro-oesophageal junctional adenocarcinoma: Where to next?Recent studies of 5-fluorouracil resistance in pancreatic cancerFluoropyrimidine and platinum toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses.Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP.Conditioned media from human macrophages of M1 phenotype attenuate the cytotoxic effect of 5‑fluorouracil on the HT‑29 colon cancer cell line.Intrinsic properties of tumour cells have a key impact on the bystander effect mediated by genetically engineered mesenchymal stromal cells.Pharmacogenetic landscape of DPYD variants in south Asian populations by integration of genome-scale data.Pathway analysis of genetic variants in folate-mediated one-carbon metabolism-related genes and survival in a prospectively followed cohort of colorectal cancer patients
P2860
Q28534572-0F5D7059-4AA5-4D17-97EB-C44E5A9E5ACDQ34008793-0EF2906E-D336-4255-9D03-AC89F7DCA0AEQ34216563-E06A7718-78F3-4529-9AE9-480A83DB318DQ34473493-8B65908E-4987-47FF-B037-F590A9EC4C48Q34653433-A4A9BFFB-DF65-4CBA-A1FD-1816BF45E3E4Q34696515-D2DE2B8A-1268-4D94-AE13-75A7E31D7C4BQ34761753-EEA03F22-EF91-4C1E-A9A8-9EF0E5E9014EQ37580393-D507A823-DA94-41BF-80C3-B581BED92347Q37630091-58753567-057D-4279-8EC4-1CE7208AA3F4Q38220816-090BA1CA-34EB-49FB-9BBB-8F41EE047803Q38268619-49063C48-0E79-4740-8FC6-5DEBF805FC7BQ38740840-D019975E-E5D6-42A3-BD6D-ED855F60B795Q38932327-E7A81FD1-DD0B-4007-9578-AD74000FB0F0Q38948535-3CECE8C2-C481-4C70-A937-7865E5DC2836Q39245263-6FA79654-A24D-4F88-8B75-FB14406F1C05Q47312464-87C3B56A-D50A-432A-83EE-372B6B6F865FQ56089175-CAC8808C-9A20-4C95-94FA-771FAAC8112A
P2860
5-Fluorouracil pharmacogenomics: still rocking after all these years?
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
5-Fluorouracil pharmacogenomics: still rocking after all these years?
@en
5-Fluorouracil pharmacogenomics: still rocking after all these years?
@nl
type
label
5-Fluorouracil pharmacogenomics: still rocking after all these years?
@en
5-Fluorouracil pharmacogenomics: still rocking after all these years?
@nl
prefLabel
5-Fluorouracil pharmacogenomics: still rocking after all these years?
@en
5-Fluorouracil pharmacogenomics: still rocking after all these years?
@nl
P2093
P2860
P50
P356
P1433
P1476
5-Fluorouracil pharmacogenomics: still rocking after all these years?
@en
P2093
Alessandro Bittoni
Michela Del Prete
Riccardo Giampieri
P2860
P304
P356
10.2217/PGS.10.167
P577
2011-02-01T00:00:00Z