Membrane and surface interactions of Alzheimer's Aβ peptide--insights into the mechanism of cytotoxicity.
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The toxicity of amyloid β oligomersTransient dynamics of Aβ contribute to toxicity in Alzheimer's diseaseDementia of the eye: the role of amyloid beta in retinal degenerationThe relationship between amyloid structure and cytotoxicityHeat shock transcription factor 1 as a therapeutic target in neurodegenerative diseasesDimer formation enhances structural differences between amyloid β-protein (1-40) and (1-42): an explicit-solvent molecular dynamics studyβ2-Microglobulin amyloid fibril-induced membrane disruption is enhanced by endosomal lipids and acidic pHAnti-Viral Properties of Amyloid-β Peptides.Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration.Super-resolution fluorescence of huntingtin reveals growth of globular species into short fibers and coexistence of distinct aggregatesEffects of membrane interaction and aggregation of amyloid β-peptide on lipid mobility and membrane domain structure.The effect of Aβ on IAPP aggregation in the presence of an isolated β-cell membrane.Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.Activity and architecture of pyroglutamate-modified amyloid-β (AβpE3-42) poresDisordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs.Interaction structure of the complex between neuroprotective factor humanin and Alzheimer's β-amyloid peptide revealed by affinity mass spectrometry and molecular modeling.Interactions between amyloid-β and Tau fragments promote aberrant aggregates: implications for amyloid toxicityMechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane.Role of the fast kinetics of pyroglutamate-modified amyloid-β oligomers in membrane binding and membrane permeability.Multivariate analyses of amyloid-beta oligomer populations indicate a connection between pore formation and cytotoxicityCurcumin reduces amyloid fibrillation of prion protein and decreases reactive oxidative stressLysophospholipid-containing membranes modulate the fibril formation of the repeat domain of a human functional amyloid, pmel17.A brief overview of amyloids and Alzheimer's disease.The interaction between amyloid-β peptides and anionic lipid membranes containing cholesterol and melatoninInteraction of Aβ(25-35) fibrillation products with mitochondria: Effect of small-molecule natural products.Gelsolin Amyloidogenesis Is Effectively Modulated by Curcumin and Emetine Conjugated PLGA Nanoparticles.Bayesian graphical network analyses reveal complex biological interactions specific to Alzheimer's diseaseA Kinetic Model for Cell Damage Caused by Oligomer Formation.Single-particle characterization of Aβ oligomers in solution.Nucleic acid-containing amyloid fibrils potently induce type I interferon and stimulate systemic autoimmunity.Europium as an inhibitor of Amyloid-β(1-42) induced membrane permeationSoluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease.Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons.Membrane permeation induced by aggregates of human islet amyloid polypeptidesThe Alzheimer's-related amyloid beta peptide is internalised by R28 neuroretinal cells and disrupts the microtubule associated protein 2 (MAP-2).Context dependence of protein misfolding and structural strains in neurodegenerative diseases.Pore formation by human stefin B in its native and oligomeric states and the consequent amyloid induced toxicity.Histone methylation in the nervous system: functions and dysfunctions.Review: membrane-associated misfolded protein propagation in natural transmissible spongiform encephalopathies (TSEs), synthetic prion diseases and Alzheimer's disease.Amyloid-β peptides in interaction with raft-mime model membranes: a neutron reflectivity insight.
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Membrane and surface interactions of Alzheimer's Aβ peptide--insights into the mechanism of cytotoxicity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 26 July 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Membrane and surface interacti ...... the mechanism of cytotoxicity.
@en
Membrane and surface interacti ...... the mechanism of cytotoxicity.
@nl
type
label
Membrane and surface interacti ...... the mechanism of cytotoxicity.
@en
Membrane and surface interacti ...... the mechanism of cytotoxicity.
@nl
prefLabel
Membrane and surface interacti ...... the mechanism of cytotoxicity.
@en
Membrane and surface interacti ...... the mechanism of cytotoxicity.
@nl
P2860
P1433
P1476
Membrane and surface interacti ...... the mechanism of cytotoxicity.
@en
P2860
P304
P356
10.1111/J.1742-4658.2011.08228.X
P407
P577
2011-07-26T00:00:00Z