Drug targets: single-cell transcriptomics hastens unbiased discovery - sprookjes - yvandenbroek - TriplyDB

Drug targets: single-cell transcriptomics hastens unbiased discovery

Drug targets: single-cell transcriptomics hastens unbiased discovery

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Quantitative biology of single neurons The concept of allosteric interaction and its consequences for the chemistry of the brain A molecular perspective on TH2-promoting cytokine receptors in patients with allergic disease.Depression-like behavior in rat: Involvement of galanin receptor subtype 1 in the ventral periaqueductal gray.Computational Systems Biology of Psoriasis: Are We Ready for the Age of Omics and Systems Biomarkers?Modulating neuromodulation by receptor membrane traffic in the endocytic pathway.Mouse TU tagging: a chemical/genetic intersectional method for purifying cell type-specific nascent RNA.Distinct features of neurotransmitter systems in the human brain with focus on the galanin system in locus coeruleus and dorsal raphe.Serotonergic neuron regulation informed by in vivo single-cell transcriptomics.Deciphering the single-cell omic: innovative application for translational medicine.Making a big thing of a small cell--recent advances in single cell analysis.Phenotype Classification Using Moment Features of Single-Cell Data.

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Drug targets: single-cell transcriptomics hastens unbiased discovery

http://www.wikidata.org/entity/Q37950158

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article científic

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Drug targets: single-cell transcriptomics hastens unbiased discovery

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Drug targets: single-cell transcriptomics hastens unbiased discovery.

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Drug targets: single-cell transcriptomics hastens unbiased discovery

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Drug targets: single-cell transcriptomics hastens unbiased discovery.

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Drug targets: single-cell transcriptomics hastens unbiased discovery

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Drug targets: single-cell transcriptomics hastens unbiased discovery.

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J.TIPS.2011.09.006

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Trends in Pharmacological Sciences

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Drug targets: single-cell transcriptomics hastens unbiased discovery

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James Eberwine

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Peter T Buckley

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mRNA-Seq whole-transcriptome analysis of a single cell

The Allen Brain Atlas: 5 years and beyond.

Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapies

The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia.

Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue.

Characterization of mRNA expression in single neurons.

Analysis of gene expression in single live neurons

Imaging the glutamate system in humans: relevance to drug discovery for schizophrenia.

Insulin causes hyperthermia by direct inhibition of warm-sensitive neurons.

Single cell transcriptomics of hypothalamic warm sensitive neurons that control core body temperature and fever response Signaling asymmetry and an extension of chemical neuroanatomy.

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10.1016/J.TIPS.2011.09.006

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51750685

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