Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.
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The cellular and physiological functions of the Lowe syndrome protein OCRL1Protein trafficking defects in inherited kidney diseasesPhosphoinositides: tiny lipids with giant impact on cell regulationOCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates.PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinityThe oculocerebrorenal syndrome of Lowe: an updateSac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.Synaptojanin cooperates in vivo with endophilin through an unexpected mechanism.The Concise Guide to PHARMACOLOGY 2013/14: enzymes.Optogenetic control of phosphoinositide metabolism.Identification of inhibitors of inositol 5-phosphatases through multiple screening strategies.Primary cilia signaling mediates intraocular pressure sensation.A role for eisosomes in maintenance of plasma membrane phosphoinositide levels.A human phospholipid phosphatase activated by a transmembrane control module.A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells.The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule.Fig4 deficiency: a newly emerged lysosomal storage disorder?PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanomaPhosphatidylinositol 3-phosphates-at the interface between cell signalling and membrane traffic.Potential mechanisms of aberrant DNA hypomethylation on the x chromosome in uterine leiomyomas.Lowe syndrome: a single center's experience in Korea.Phosphoinositides and cytokinesis: the "PIP" of the iceberg.Membrane trafficking components in cytokinesis.Phosphatidylinositol 4-kinases and PI4P metabolism in the nervous system: roles in psychiatric and neurological diseases.Mitotic inhibition of clathrin-mediated endocytosis.Phagocytosis and cytokinesis: do cells use common tools to cut and to eat? Highlights on common themes and differences.Biochemistry and structure of phosphoinositide phosphatases.Rab35: GEFs, GAPs and effectors.Inositol lipid phosphatases in membrane trafficking and human disease.Structures of Ras superfamily effector complexes: What have we learnt in two decades?Rab35 GTPase: A Central Regulator of Phosphoinositides and F-actin in Endocytic Recycling and Beyond.How does SHIP1/2 balance PtdIns(3,4)P2 and does it signal independently of its phosphatase activity?Long-term renal outcome in children with OCRL mutations: retrospective analysis of a large international cohort.Expression, Purification, Crystallisation and X-ray Crystallographic Analysis of a Truncated Form of Human Src Homology 2 Containing Inositol 5-Phosphatase 2.Evidence of a role of inositol polyphosphate 5-phosphatase INPP5E in cilia formation in zebrafishWhen worlds collide: inositol pyrophosphates and phosphoinositides intersect at the plasma membrane.Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons.The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors.Loss of OCRL increases ciliary PI(4,5)P2 in Lowe oculocerebrorenal syndrome.
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Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.
description
article científic
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article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.
@en
Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.
@nl
type
label
Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.
@en
Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.
@nl
prefLabel
Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.
@en
Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.
@nl
P2860
P1476
Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.
@en
P2093
Michelle Pirruccello
P2860
P304
P356
10.1016/J.TIBS.2012.01.002
P577
2012-02-28T00:00:00Z