Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modeling. - sprookjes - yvandenbroek - TriplyDB

Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modeling.

Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modeling.

http://www.wikidata.org/entity/Q37998107

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Blood brain barrier: An overview on strategies in drug delivery, realistic in vitro modeling and in vivo live tracking Drug delivery systems, CNS protection, and the blood brain barrier Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitro models of the rat blood-brain barrier and blood-spinal cord barrier.Blood-brain barrier modeling: challenges and perspectives.Improving the prediction of drug disposition in the brain.Transendothelial Transport and Its Role in Therapeutics.De novo prediction of p-glycoprotein-mediated efflux liability for druglike compounds.Probabilistic Approach to Generating MPOs and Its Application as a Scoring Function for CNS Drugs.

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P2860

Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modeling.

http://www.wikidata.org/entity/Q37998107

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article scientifique

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Strategies to minimize CNS tox ...... ys and computational modeling.

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Strategies to minimize CNS tox ...... ys and computational modeling.

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Strategies to minimize CNS tox ...... ys and computational modeling.

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Strategies to minimize CNS tox ...... ys and computational modeling.

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Strategies to minimize CNS tox ...... ys and computational modeling.

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Strategies to minimize CNS tox ...... ys and computational modeling.

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17425255.2012.677028

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Expert Opinion on Drug Metabolism & Toxicology

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Strategies to minimize CNS tox ...... ys and computational modeling.

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Jennifer L Liras

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Patrick Trapa

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Scot Mente

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Travis T Wager

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P2860

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Blood-brain barrier alterations in ageing and dementia

5-fluorouracil-induced leukoencephalopathy in patients with breast cancer

Defining desirable central nervous system drug space through the alignment of molecular properties, in vitro ADME, and safety attributes

Knowledge-Based, Central Nervous System (CNS) Lead Selection and Lead Optimization for CNS Drug Discovery

H1-antihistamine up-dosing in chronic spontaneous urticaria: patients' perspective of effectiveness and side effects--a retrospective survey study

Structure and function of the blood-brain barrier

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531-542

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scholarly article

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10.1517/17425255.2012.677028

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2012-03-29T00:00:00Z

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22458547

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