Regulation of the transforming growth factor β pathway by reversible ubiquitylation.
about
Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signallingUSP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.Activin A regulates activation of mouse neutrophils by Smad3 signallingUbiquitin-specific proteases as therapeutic targets for the treatment of breast cancerUSP11 augments TGFβ signalling by deubiquitylating ALK5.OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3.Ubiquitin carboxyl-terminal hydrolase-L5 promotes TGFβ-1 signaling by de-ubiquitinating and stabilizing Smad2/Smad3 in pulmonary fibrosisBcl-3 regulates TGFβ signaling by stabilizing Smad3 during breast cancer pulmonary metastasis.Deubiquitylases from genes to organism.Crosstalk between kinases and Nedd4 family ubiquitin ligases.The E3 ligase Itch in immune regulation and beyond.Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization.The TGFβ-induced phosphorylation and activation of p38 mitogen-activated protein kinase is mediated by MAP3K4 and MAP3K10 but not TAK1.Targeting endogenous proteins for degradation through the affinity-directed protein missile system.
P2860
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P2860
Regulation of the transforming growth factor β pathway by reversible ubiquitylation.
description
article científic
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article scientifique
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articol științific
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articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Regulation of the transforming growth factor β pathway by reversible ubiquitylation.
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type
label
Regulation of the transforming growth factor β pathway by reversible ubiquitylation.
@en
prefLabel
Regulation of the transforming growth factor β pathway by reversible ubiquitylation.
@en
P2860
P921
P356
P1433
P1476
Regulation of the transforming growth factor β pathway by reversible ubiquitylation.
@en
P2093
Gopal P Sapkota
Lina Herhaus
P2860
P304
P356
10.1098/RSOB.120082
P577
2012-05-01T00:00:00Z