Dihydrofolate reductase as a therapeutic target for infectious diseases: opportunities and challenges.

Dihydrofolate reductase as a therapeutic target for infectious diseases: opportunities and challenges.

Item
http://www.wikidata.org/entity/Q38026606
First Three-Dimensional Structure of Toxoplasma gondii Thymidylate Synthase–Dihydrofolate Reductase: Insights for Catalysis, Interdomain Interactions, and Substrate ChannelingStructure of Dihydromethanopterin Reductase, a Cubic Protein Cage for Redox TransferMorphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of actionPreliminary joint X-ray and neutron protein crystallographic studies of ecDHFR complexed with folate and NADP+.Molecular Characteristics and Serodiagnostic Potential of Dihydrofolate Reductase from Echinococcus granulosus.A Focused Screen Identifies Antifolates with Activity on Mycobacterium tuberculosis.New Structural Templates for Clinically Validated and Novel Targets in Antimicrobial Drug Research and Development.Thermodynamic and functional characteristics of deep-sea enzymes revealed by pressure effects.Synthesis, Antitumor Evaluation and Molecular Docking of New Morpholine Based Heterocycles.Synthesis, Biological Evaluation and Molecular Docking Studies of 6-Aryl-2-Styrylquinazolin-4(3H)-Ones.Structure-based analysis of Bacilli and plasmid dihydrofolate reductase evolution.Understanding the molecular mechanism of substrate channeling and domain communication in protozoal bifunctional TS-DHFR.Cloning, recombinant expression and inhibitor profiles of dihydrofolate reductase from the Australian sheep blow fly, Lucilia cuprina.5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents.Expression, purification, and inhibition profile of dihydrofolate reductase from the filarial nematode Wuchereria bancrofti.
P2860

Dihydrofolate reductase as a therapeutic target for infectious diseases: opportunities and challenges.

Item
http://www.wikidata.org/entity/Q38026606
description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Dihydrofolate reductase as a t ...... opportunities and challenges.
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type
label
Dihydrofolate reductase as a t ...... opportunities and challenges.
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prefLabel
Dihydrofolate reductase as a t ...... opportunities and challenges.
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P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P356
P1433
P1476
Dihydrofolate reductase as a t ...... opportunities and challenges.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698