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Raf kinase inhibitory protein (RKIP) as a metastasis suppressor: regulation of signaling networks in cancerDidymin: an orally active citrus flavonoid for targeting neuroblastoma.Loss of Raf-1 kinase inhibitory protein delays early-onset severe retinal ciliopathy in Cep290rd16 mouse.Raf kinase inhibitor protein inhibits cholangiocarcinoma cell metastasis by downregulating matrix metalloproteinase 9 and upregulating tissue inhibitor of metalloproteinase 4 expression.Differential proteomic profiling unveils new molecular mechanisms associated with mitochondrial complex III deficiency.RKIP phosphorylation and STAT3 activation is inhibited by oxaliplatin and camptothecin and are associated with poor prognosis in stage II colon cancer patients.Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer.Comparative RNA seq analysis of the New Zealand glowworm Arachnocampa luminosa reveals bioluminescence-related genes.Increased Expression of miR-23a Mediates a Loss of Expression in the RAF Kinase Inhibitor Protein RKIP.Matrix Metalloproteinase 10 Degradomics in Keratinocytes and Epidermal Tissue Identifies Bioactive Substrates With Pleiotropic FunctionsRKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration.Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity.Proteomics analysis of human tears from aqueous-deficient and evaporative dry eye patients.Clinical implications for loss or diminution of expression of Raf-1 kinase inhibitory protein and its phosphorylated form in ductal breast cancerLoss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC)Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted protein and has multiple functions.Dihydroartemisinin induces apoptosis of cervical cancer cells via upregulation of RKIP and downregulation of bcl-2MicroRNA-224: as a potential target for miR-based therapy of cancer.Specific regulation of PRMT1 expression by PIAS1 and RKIP in BEAS-2B epithelia cells and HFL-1 fibroblasts in lung inflammation.Raf kinase inhibitor protein (RKIP) inhibits the cell migration and invasion in human glioma cell lines in vitro.RKIP promotes cisplatin-induced gastric cancer cell death through NF-κB/Snail pathway.Raf kinase inhibitor protein (RKIP) deficiency decreases latency of tumorigenesis and increases metastasis in a murine genetic model of prostate cancer.RKIP inhibits gastric cancer cell survival and invasion by regulating the expression of HMGA2 and OPN.RKIP suppresses gastric cancer cell proliferation and invasion and enhances apoptosis regulated by microRNA-224.Expression of RKIP in chronic myelogenous leukemia K562 cell and inhibits cell proliferation by regulating the ERK/MAPK pathway.Crosstalks between Raf-kinase inhibitor protein and cancer stem cell transcription factors (Oct4, KLF4, Sox2, Nanog).Overexpression of RKIP and its cross-talk with several regulatory gene products in multiple myeloma.RKIP and TBK1 form a positive feedback loop to promote type I interferon production in innate immunity.Raf kinase inhibitor protein regulates oxygen-glucose deprivation-induced PC12 cells apoptosis through the NF-κB and ERK pathways.Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein.Raf kinase inhibitory protein role in the molecular subtyping of breast cancer.Phosphatidylethanolamine binding protein 1 in vacular endothelial cell autophagy and atherosclerosis.Raf Kinase Inhibitor Protein Attenuates Ischemic-Induced Microglia Cell Apoptosis and Activation Through NF-κB Pathway.UHPLC-Q-TOF-MS based serum metabonomics revealed the metabolic perturbations of ischemic stroke and the protective effect of RKIP in rat models.Loss of RKIP is a frequent event in myeloid sarcoma and promotes leukemic tissue infiltration.RKIP: A Key Regulator in Tumor Metastasis Initiation and Resistance to Apoptosis: Therapeutic Targeting and ImpactRaf kinase inhibitor protein mediates myocardial fibrosis under conditions of enhanced myocardial oxidative stress
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
RKIP: much more than Raf kinase inhibitory protein.
@en
type
label
RKIP: much more than Raf kinase inhibitory protein.
@en
prefLabel
RKIP: much more than Raf kinase inhibitory protein.
@en
P2093
P2860
P356
P1476
RKIP: much more than Raf kinase inhibitory protein.
@en
P2093
Kam C Yeung
Milad S Bitar
Zainab Taqi
P2860
P304
P356
10.1002/JCP.24335
P577
2013-08-01T00:00:00Z