The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.
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Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related DiseasesHistone methylations in heart development, congenital and adult heart diseases8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase InhibitorsKDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage.Genome-Wide Loss of Heterozygosity and DNA Copy Number Aberration in HPV-Negative Oral Squamous Cell Carcinoma and Their Associations with Disease-Specific Survival.KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes.Integrated genomic and functional analyses of histone demethylases identify oncogenic KDM2A isoform in breast cancer.KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model.Epigenetics of oropharyngeal squamous cell carcinoma: opportunities for novel chemotherapeutic targets.Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential.KDM4 histone demethylase inhibitors for anti-cancer agents: a patent review.Epigenomic analysis in a cell-based model reveals the roles of H3K9me3 in breast cancer transformation.JARID1B modulates lung cancer cell proliferation and invasion by regulating p53 expression.Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation.Pyrido[3,4-d]pyrimidin-4(3H)-one metabolism mediated by aldehyde oxidase is blocked by C2-substitutionHistoneH3 demethylase JMJD2A promotes growth of liver cancer cells through up-regulating miR372.Enhancement of Proliferation and Invasion of Gastric Cancer Cell by KDM5C Via Decrease in p53 Expression.GPS2/KDM4A pioneering activity regulates promoter-specific recruitment of PPARγ.Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.The JmjN domain as a dimerization interface and a targeted inhibitor of KDM4 demethylase activity.
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P2860
The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.
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article científic
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The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.
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type
label
The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.
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prefLabel
The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.
@en
P2860
P356
P1476
The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.
@en
P2093
Leah C Young
Michael J Hendzel
P2860
P304
P356
10.1139/BCB-2012-0054
P577
2012-12-05T00:00:00Z