Understanding the transport properties of metabolites: case studies and considerations for drug development.
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The role of transporters in toxicity and diseaseIn vivo and in vitro metabolites from the main diester and monoester diterpenoid alkaloids in a traditional chinese herb, the aconitum speciesThe Use of In Vitro Data and Physiologically-Based Pharmacokinetic Modeling to Predict Drug Metabolite Exposure: Desipramine Exposure in Cytochrome P4502D6 Extensive and Poor Metabolizers Following Administration of Imipramine.Role of multidrug resistance-associated protein 4 in the basolateral efflux of hepatically derived enalaprilat.Methylation and its role in the disposition of tanshinol, a cardiovascular carboxylic catechol from Salvia miltiorrhiza roots (Danshen).Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitisA review of designer anabolic steroids in equine sports.Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites.Managing drug-drug interactions with new direct-acting antiviral agents in chronic hepatitis C.Effect of hesperidin on the pharmacokinetics of CPT-11 and its active metabolite SN-38 by regulating hepatic Mrp2 in rats.Physiologically Based Pharmacokinetic Modelling with Dynamic PET Data to Study the In Vivo Effects of Transporter Inhibition on Hepatobiliary Clearance in Mice.Effect of Korean Red Ginseng extracts on drug-drug interactions.Glucuronidation: driving factors and their impact on glucuronide disposition
P2860
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P2860
Understanding the transport properties of metabolites: case studies and considerations for drug development.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Understanding the transport pr ...... erations for drug development.
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type
label
Understanding the transport pr ...... erations for drug development.
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prefLabel
Understanding the transport pr ...... erations for drug development.
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P2093
P356
P1476
Understanding the transport pr ...... derations for drug development
@en
P2093
Maciej J Zamek-Gliszczynski
Mary F Paine
Xiaoyan Chu
P304
P356
10.1124/DMD.113.055558
P577
2013-12-17T00:00:00Z