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7α, 25-dihydroxycholesterol-mediated activation of EBI2 in immune regulation and diseasesFunctional Stability of the Human Kappa Opioid Receptor Reconstituted in Nanodiscs Revealed by a Time-Resolved Scintillation Proximity AssayThe role of experimental and computational structural approaches in 7TM drug discovery.Triggering the succinate receptor GPR91 enhances pressure overload-induced right ventricular hypertrophy.Discovery of GPCR ligands for probing signal transduction pathways.A desirability function-based scoring scheme for selecting fragment-like class A aminergic GPCR ligands.New paradigms in GPCR drug discovery.Novel approaches for targeting the adenosine A2A receptor.Identifying ligands at orphan GPCRs: current status using structure-based approaches.Expanding the horizons of G protein-coupled receptor structure-based ligand discovery and optimization using homology models.What can we learn from molecular dynamics simulations for GPCR drug design?Methods for Virtual Screening of GPCR Targets: Approaches and Challenges.Activation processes in ligand-activated G protein-coupled receptors: A case study of the adenosine A2A receptor.Dim-light photoreceptor of chub mackerel Scomber japonicus and the photoresponse upon illumination with LEDs of different wavelengths.Efficient cell pairing in droplets using dual-color sorting.Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design.Structure-based virtual screening for fragment-like ligands of the G protein-coupled histamine H4 receptor
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Structure-based and fragment-based GPCR drug discovery.
@en
type
label
Structure-based and fragment-based GPCR drug discovery.
@en
prefLabel
Structure-based and fragment-based GPCR drug discovery.
@en
P2093
P2860
P356
P1433
P1476
Structure-based and fragment-based GPCR drug discovery.
@en
P2093
Giles A Brown
John A Christopher
Stephen P Andrews
P2860
P304
P356
10.1002/CMDC.201300382
P577
2013-12-18T00:00:00Z