Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; translational safety considerations.
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Inhibition of the fibroblast growth factor receptor (FGFR) pathway: the current landscape and barriers to clinical applicationFibroblast growth factor receptor 4 protein expression and clinicopathological features in gastric cancer.FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3β/β- catenin signaling cascade via FGFR4 activation.Identification of FGF19 as a prognostic marker and potential driver gene of lung squamous cell carcinomas in Chinese smoking patientsTrichlorobenzene-substituted azaaryl compounds as novel FGFR inhibitors exhibiting potent antitumor activity in bladder cancer cells in vitro and in vivoTargeting fibroblast growth factor 19 in liver disease: a potential biomarker and therapeutic target.Novel therapeutic targets and predictive markers for hepatocellular carcinoma.New therapeutic concepts in bile acid transport and signaling for management of cholestasis.Increased Expression of FGF19 Contributes to Tumor Progression and Cell Motility of Human Thyroid Cancer.Targeting FGF19/FGFR4 Pathway: A Novel Therapeutic Strategy for Hepatocellular Carcinoma.Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease.Mechanistic target of rapamycin complex 1 is an essential mediator of metabolic and mitogenic effects of fibroblast growth factor 19 in hepatoma cells.FGF19 genetic amplification as a potential therapeutic target in lung squamous cell carcinomas.Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis.
P2860
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P2860
Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; translational safety considerations.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
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name
Targeted inhibition of the FGF ...... ational safety considerations.
@en
type
label
Targeted inhibition of the FGF ...... ational safety considerations.
@en
prefLabel
Targeted inhibition of the FGF ...... ational safety considerations.
@en
P2860
P356
P1433
P1476
Targeted inhibition of the FGF ...... ational safety considerations.
@en
P2093
Howard R Mellor
P2860
P356
10.1111/LIV.12462
P577
2014-01-24T00:00:00Z