B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements.
about
Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signallingImmunological aspects in chronic lymphocytic leukemia (CLL) developmentB cell receptor editing in tolerance and autoimmunityRoles of the NF-kappaB pathway in lymphocyte development and function.Activation of Ras overcomes B-cell tolerance to promote differentiation of autoreactive B cells and production of autoantibodiesBAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signalingCentral B-cell tolerance: where selection begins.Multiple factors influence the contribution of individual immunoglobulin light chain genes to the naïve antibody repertoireThe development of mature B lymphocytes requires the combined function of CD19 and the p110δ subunit of PI3KTargeting Anti-Insulin B Cell Receptors Improves Receptor Editing in Type 1 Diabetes-Prone Mice.RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetesMechanisms controlling expression of the RAG locus during lymphocyte development.NF-kappaB activity marks cells engaged in receptor editing.Functional silencing is initiated and maintained in immature anti-insulin B cellsAntigen and cytokine receptor signals guide the development of the naïve mature B cell repertoire.Dual immunoglobulin light chain B cells: Trojan horses of autoimmunity?Role of PI3K in the generation and survival of B cells.NF-κB function in B lymphocytes.B-lymphocyte tolerance and effector function in immunity and autoimmunity.Mechanisms of central tolerance for B cells.Calcium Signaling: From Normal B Cell Development to Tolerance Breakdown and Autoimmunity.Direct reduction of antigen receptor expression in polyclonal B cell populations developing in vivo results in light chain receptor editing.HM71224, a selective Bruton's tyrosine kinase inhibitor, attenuates the development of murine lupus.Tonic BCR signaling represses receptor editing via Raf- and calcium-dependent signaling pathways.Bruton's Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus.
P2860
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P2860
B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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2008年學術文章
@zh-hant
name
B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements.
@en
type
label
B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements.
@en
prefLabel
B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements.
@en
P2093
P1476
B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements.
@en
P2093
Amanda L Vegoe
Brian R Schram
Jiabin Liu
Keli L Hippen
Lina E Tze
Lydia Najera
Richard R Hardy
Timothy W Behrens
P304
P356
10.4049/JIMMUNOL.180.7.4728
P407
P577
2008-04-01T00:00:00Z