Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognition by XPC.
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Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligaseMonoubiquitinated histone H2A destabilizes photolesion-containing nucleosomes with concomitant release of UV-damaged DNA-binding protein E3 ligaseStructural basis of UV DNA-damage recognition by the DDB1-DDB2 complexIncreased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome miceDamaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repairXPC: Going where no DNA damage sensor has gone beforeBood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferaseRegulation and role of Arabidopsis CUL4-DDB1A-DDB2 in maintaining genome integrity upon UV stressCul4A is required for hematopoietic cell viability and its deficiency leads to apoptosisSingle-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates.Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites.Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein.In vivo destabilization and functional defects of the xeroderma pigmentosum C protein caused by a pathogenic missense mutationRepair of laser-localized DNA interstrand cross-links in G1 phase mammalian cellsCC3/TIP30 affects DNA damage repair.Transcription factor Etv5 is essential for the maintenance of alveolar type II cells.Dissociation of CAK from core TFIIH reveals a functional link between XP-G/CS and the TFIIH disassembly state.Photo-cross-linking of XPC-Rad23B to cisplatin-damaged DNA reveals contacts with both strands of the DNA duplex and spans the DNA adduct.RETRACTED: DDB2, an essential mediator of premature senescenceDDB2 suppresses tumorigenicity by limiting the cancer stem cell population in ovarian cancer.The role of XPC: implications in cancer and oxidative DNA damageCrossover localisation is regulated by the neddylation posttranslational regulatory pathway.Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNANER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinases to DNA damage sitesUbiquitin-specific protease 7 regulates nucleotide excision repair through deubiquitinating XPC protein and preventing XPC protein from undergoing ultraviolet light-induced and VCP/p97 protein-regulated proteolysis.Overexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmenting cellular apoptosis.The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stability.Damaged DNA-binding protein down-regulates epigenetic mark H3K56Ac through histone deacetylase 1 and 2.Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cellsCUL4A overexpression enhances lung tumor growth and sensitizes lung cancer cells to erlotinib via transcriptional regulation of EGFR.Orchestral maneuvers at the damaged sites in nucleotide excision repair.p21 cooperates with DDB2 protein in suppression of ultraviolet ray-induced skin malignancies.DDB2 promotes chromatin decondensation at UV-induced DNA damage.Cul4A is an oncogene in malignant pleural mesothelioma.Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repairMolecular mechanisms of xeroderma pigmentosum (XP) proteins.Damaged DNA binding protein 2 in reactive oxygen species (ROS) regulation and premature senescenceLack of CAK complex accumulation at DNA damage sites in XP-B and XP-B/CS fibroblasts reveals differential regulation of CAK anchoring to core TFIIH by XPB and XPD helicases during nucleotide excision repair.Valosin-containing Protein (VCP)/p97 Segregase Mediates Proteolytic Processing of Cockayne Syndrome Group B (CSB) in Damaged Chromatin.Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase
P2860
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P2860
Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognition by XPC.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Cullin 4A-mediated proteolysis ...... ivo lesion recognition by XPC.
@en
type
label
Cullin 4A-mediated proteolysis ...... ivo lesion recognition by XPC.
@en
prefLabel
Cullin 4A-mediated proteolysis ...... ivo lesion recognition by XPC.
@en
P2093
P2860
P356
P1476
Cullin 4A-mediated proteolysis ...... ivo lesion recognition by XPC.
@en
P2093
Altaf A Wani
Gulzar Wani
Mette Praetorius-Ibba
Mohamed A El-Mahdy
Qi-en Wang
Qianzheng Zhu
P2860
P304
13404-13411
P356
10.1074/JBC.M511834200
P407
P577
2006-03-08T00:00:00Z