about
Understanding anti-tuberculosis drug efficacy: rethinking bacterial populations and how we model themCytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputumBenzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesisInactivation of polyketide synthase and related genes results in the loss of complex lipids in Mycobacterium tuberculosis H37RvcDNA-RNA subtractive hybridization reveals increased expression of mycocerosic acid synthase in intracellular Mycobacterium bovis BCG.Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-gamma.Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages.Microarray analysis of defined Mycobacterium tuberculosis populations using RNA amplification strategies.Dissecting interferon-induced transcriptional programs in human peripheral blood cells.Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophagesOleoyl coenzyme A regulates interaction of transcriptional regulator RaaS (Rv1219c) with DNA in mycobacteria.Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states.RNA profiling in host-pathogen interactions.Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages.Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy.Quantification of global transcription patterns in prokaryotes using spotted microarraysMicroarray analysis of whole genome expression of intracellular Mycobacterium tuberculosis.A non-canonical mismatch repair pathway in prokaryotesAdjusting to a new home: Mycobacterium tuberculosis gene expression in response to an intracellular lifestyle.Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions.Methionine sulfoximine resistance in Mycobacterium tuberculosis is due to a single nucleotide deletion resulting in increased expression of the major glutamine synthetase, GlnA1.Examining the basis of isoniazid tolerance in nonreplicating Mycobacterium tuberculosis using transcriptional profiling.Whole genome analysis using microarrays.The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds.Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function.Intestinal injury and endotoxemia in children undergoing surgery for congenital heart disease.A Novel TetR-Like Transcriptional Regulator Is Induced in Acid-Nitrosative Stress and Controls Expression of an Efflux Pump in Mycobacteria.Increased transcription of a potential sigma factor regulatory gene Rv1364c in Mycobacterium bovis BCG while residing in macrophages indicates use of alternative promoters.Distance-based differential analysis of gene curves.Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death.Transcriptional Profiling Mycobacterium tuberculosis from Patient Sputa.Myocardial depressant effects of interleukin 6 in meningococcal sepsis are regulated by p38 mitogen-activated protein kinase.Effects of low incubation temperatures on the bactericidal activity of anti-tuberculosis drugsReprogramming the Mycobacterium tuberculosis transcriptome during pathogenesisUse of DNA Arrays to Study Transcriptional Responses to Antimycobacterial CompoundsProtein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112Whole genome sequencing of drug resistant Mycobacterium tuberculosis isolates from a high burden tuberculosis region of North West PakistanDesign, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer ChannelIdentification of antigens presented by MHC for vaccines against tuberculosis
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description
hulumtues
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հետազոտող
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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Simon J. Waddell
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P106
P1153
7003459092
P21
P31
P496
0000-0002-3684-9116