Differential recognition of response elements determines target gene specificity for p53 and p63
about
Human GGT2 does not autocleave into a functional enzyme: A cautionary tale for interpretation of microarray data on redox signalingNIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cyclep63 regulates proliferation and differentiation of developmentally mature keratinocytesTumor suppression in skin and other tissues via cross-talk between vitamin D- and p53-signalingPliable DNA Conformation of Response Elements Bound to Transcription Factor p63Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence codeThe microRNA feedback regulation of p63 in cancer progressionSCF TrCP1 activates and ubiquitylates TAp63gammaGPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent mannerThe coordinated p53 and estrogen receptor cis-regulation at an FLT1 promoter SNP is specific to genotoxic stress and estrogenic compoundp53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray dataNovel in vivo targets of DeltaNp63 in keratinocytes identified by a modified chromatin immunoprecipitation approachConservation of DNA-binding specificity and oligomerisation properties within the p53 family.NAD(P)H quinone oxidoreductase protects TAp63gamma from proteasomal degradation and regulates TAp63gamma-dependent growth arrest.∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.p63 directly induces expression of Alox12, a regulator of epidermal barrier formation.Induction of ΔNp63 by the newly identified keratinocyte-specific transforming growth factor β Signaling Pathway with Smad2 and IκB Kinase α in squamous cell carcinoma.Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradationDeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulationP53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements.Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and mitochondria by up-regulating the transactivating p63 isoform alpha (TAP63alpha).Ubiquitin and ubiquitin-like modifications of the p53 family.Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification.Tumor protein p63/nuclear factor κB feedback loop in regulation of cell death.Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene.Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15.p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.Functional evolution of the p53 regulatory network through its target response elements.Repression of Wnt/β-catenin response elements by p63 (TP63)A/T gap tolerance in the core sequence and flanking sequence requirements of non-canonical p53 response elementsFunctional four-base A/T gap core sequence CATTAG of P53 response elements specifically bound tetrameric P53 differently than two-base A/T gap core sequence CATG bound both dimeric and tetrameric P53DeltaNp63 antagonizes p53 to regulate mesoderm induction in Xenopus laevis.T-type Ca2+ channel expression in human esophageal carcinomas: a functional role in proliferation.Redefining the p53 response element.Growth differentiating factor 15 enhances the tumor-initiating and self-renewal potential of multiple myeloma cells.The role of p63 in cancer, stem cells and cancer stem cells.Alterations of p63 and p73 in human cancers.The role of P-cadherin in skin biology and skin pathology: lessons from the hair follicle.Functional analysis of p53 binding under differential stresses.Maintaining epithelial stemness with p63.
P2860
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P2860
Differential recognition of response elements determines target gene specificity for p53 and p63
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Differential recognition of re ...... ne specificity for p53 and p63
@en
type
label
Differential recognition of re ...... ne specificity for p53 and p63
@en
prefLabel
Differential recognition of re ...... ne specificity for p53 and p63
@en
P2093
P2860
P1476
Differential recognition of re ...... ne specificity for p53 and p63
@en
P2093
Alexey Fomenkov
Barry Trink
David Sidransky
Hannah Lui Park
Keishi Yamashita
Motonobu Osada
Myoung Sook Kim
Shuji Nomoto
Yuichi Nagakawa
P2860
P304
P356
10.1128/MCB.25.14.6077-6089.2005
P407
P577
2005-07-01T00:00:00Z