TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6. - sprookjes - yvandenbroek - TriplyDB

TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.

TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.

http://www.wikidata.org/entity/Q38367190

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HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylation Histone deacetylase 6 plays a role as a distinct regulator of diverse cellular processes Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth.Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis.Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis.Altered mRNP granule dynamics in FTLD pathogenesis.Tissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 and SIRT2 pathways.Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia.Polyglutamine (polyQ) disorders: the chromatin connection.Neurodegenerative diseases: quantitative predictions of protein-RNA interactions.Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6).A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects.Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins.Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes.Gut-derived cholecystokinin contributes to visceral hypersensitivity via nerve growth factor-dependent neurite outgrowth.TDP-43 regulates the mammalian spinogenesis through translational repression of Rac1.HDAC6 and RhoA are novel players in Abeta-driven disruption of neuronal polarity.Epigenetic profiles in polyglutamine disorders.Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions.The N Termini of TAR DNA-Binding Protein 43 (TDP43) C-Terminal Fragments Influence Degradation, Aggregation Propensity, and Morphology From Mouse Models to Human Disease: An Approach for Amyotrophic Lateral Sclerosis

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P2860

TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.

http://www.wikidata.org/entity/Q38367190

description

2011 nî lūn-bûn

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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2011年學術文章

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name

TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.

@en

type

label

TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.

@en

prefLabel

TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.

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Molecular Neurodegeneration

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TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.

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P2093

Christine Schurr

http://www.w3.org/2001/XMLSchema#string

Fabienne C Fiesel

http://www.w3.org/2001/XMLSchema#string

Philipp J Kahle

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Stephanie S Weber

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P2860

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein

Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs

A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons

Exome sequencing reveals VCP mutations as a cause of familial ALS

TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing

Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis

Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene.

Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally.

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

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10.1186/1750-1326-6-64

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6

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2011-08-30T00:00:00Z

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21878116

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3170629

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