N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester.
about
Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins.Synthesis of homogeneous MUC1 oligomers via a bi-directional ligation strategy.Shifting Native Chemical Ligation into Reverse through N→S Acyl Transfer.Unraveling the complexity of ubiquitin signalingChemical Synthesis of Phosphorylated Histone H2A at Tyr57 Reveals Insight into the Inhibition Mode of the SAGA Deubiquitinating Module.Synthetic polyubiquitinated α-Synuclein reveals important insights into the roles of the ubiquitin chain in regulating its pathophysiology.Nonenzymatic ubiquitylation.9-Fluorenylmethoxycarbonyl-based solid-phase synthesis of peptide α-thioesters.Chemistry and biology of the ubiquitin signal.Sequential native peptide ligation strategies for total chemical protein synthesis.Using chemistry to investigate the molecular consequences of protein ubiquitylation.Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation.Pushing the Boundaries of Chemical Protein Synthesis: The Case of Ubiquitin Chains and Polyubiquitinated Peptides and Proteins.Total chemical synthesis of SUMO-2-Lys63-linked diubiquitin hybrid chains assisted by removable solubilizing tags.Chemical and semisynthesis of modified histones.Chemical and semisynthetic approaches to study and target deubiquitinases.Biological and Physicochemical Functions of Ubiquitylation Revealed by Synthetic Chemistry Approaches.A one-pot three-segment ligation strategy for protein chemical synthesis.Chemical Synthesis of Ubiquitin Chains.Expanding the scope of N → S acyl transfer in native peptide sequences.One-pot chemical synthesis of small ubiquitin-like modifier protein-peptide conjugates using bis(2-sulfanylethyl)amido peptide latent thioester surrogates.A Versatile Strategy for the Semisynthetic Production of Ser65 Phosphorylated Ubiquitin and Its Biochemical and Structural CharacterisationChemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitinFacile synthesis of native and protease-resistant ubiquitylated peptides.Chemical bypass of intein-catalyzed N-S acyl shift in protein splicing.A novel post-ligation thioesterification device enables peptide ligation in the N to C direction: synthetic study of human glycodelin.Total chemical synthesis of histones and their analogs, assisted by native chemical ligation and palladium complexes.A Facile N-Mercaptoethoxyglycinamide (MEGA) Linker Approach to Peptide Thioesterification and Cyclization.Protein chemical synthesis by α-ketoacid-hydroxylamine ligation.2-nitroveratryl as a photocleavable thiol-protecting group for directed disulfide bond formation in the chemical synthesis of insulin.A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters.Generation of a Mono-ubiquitinated PCNA Mimic by Click Chemistry
P2860
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P2860
N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester.
@en
type
label
N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester.
@en
prefLabel
N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester.
@en
P2093
P2860
P356
P1476
N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester.
@en
P2093
Ashraf Brik
K S Ajish Kumar
Lesly A Erlich
Mahmood Haj-Yahya
Philip E Dawson
P2860
P304
P356
10.1039/C000332H
P577
2010-03-11T00:00:00Z