Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs).
about
Mechanochemistry: A Force of SynthesisMechanochemical synthesis of thioureas, ureas and guanidines.Nucleophilic displacement reactions of 5'-derivatised nucleosides in a vibration ball mill.Solvent-free copper-catalyzed click chemistry for the synthesis of N-heterocyclic hybrids based on quinoline and 1,2,3-triazole.Main group mechanochemistry.Solid-state mechanochemical ω-functionalization of poly(ethylene glycol).Influence of the milling parameters on the nucleophilic substitution reaction of activated β-cyclodextrins.The effect of milling frequency on a mechanochemical organic reaction monitored by in situ Raman spectroscopy.Mechanically induced oxidation of alcohols to aldehydes and ketones in ambient air: Revisiting TEMPO-assisted oxidations.Mechanochemical Ring-Opening Polymerization of Lactide: Liquid-Assisted Grinding for the Green Synthesis of Poly(lactic acid) with High Molecular Weight.Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity.MechanoAPI-ILs: Pharmaceutical Ionic Liquids Obtained through Mechanochemical Synthesis.On the mechanism of mechanochemical molecular encapsulation in peptidic capsules.Multicomponent crystals of gliclazide and tromethamine: preparation, physico-chemical, and pharmaceutical characterization.Solvent-free iodine-promoted synthesis of 3,2'-pyrrolinyl spirooxindoles from alkylidene oxindoles and enamino esters under ball-milling conditions.Carbodiimide insertion into sulfonimides: one-step route to azepine derivatives via a two-atom saccharin ring expansion.Recyclable heterogeneous metal foil-catalyzed cyclopropenation of alkynes and diazoacetates under solvent-free mechanochemical reaction conditions† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00443a.Mechanochemistry of nucleosides, nucleotides and related materials.Enthalpy vs. friction: heat flow modelling of unexpected temperature profiles in mechanochemistry of metal-organic frameworks.Mechanochemical indole synthesis by rhodium-catalysed oxidative coupling of acetanilides and alkynes under solventless conditions in a ball millMechanoenzymatic peptide and amide bond formationMechanochemistry for facilitated access to N,N-diaryl NHC metal complexes
P2860
Q28818121-BDEAD30F-10D4-4DCE-9411-BCB89A137ADFQ41598920-2998CC4B-846B-49E1-978A-6E9691B6B4DBQ41943707-12853859-3E2E-4640-B77F-5CBF701238BAQ46253119-24A996C4-1387-4235-88F8-F92E07DD44E4Q46593295-AC101E7F-618A-4765-B381-C684D1AD424FQ47093919-C1AF0C78-0029-49F6-A5FC-0EF78A11BA86Q47095072-7679E8EE-A1B3-492D-AB63-C2DE7DFD87D2Q47124946-608F536F-3B04-4858-A802-C63FCCF3EFBAQ47130855-71FACADC-C532-428E-A03F-C09BD99B1CB6Q47206328-E50DCF78-06B9-4C4C-901A-03B8E1C31E6FQ47729001-50AECD2D-20EE-4A01-8D30-C100C08FFC6DQ48233703-DA2D636E-4F22-4BF4-B1CC-630EF0EA5482Q48300143-4F4FBE17-449E-4746-83AD-B336D207622FQ49687596-4D43BEAF-4E26-45F8-8DEF-9642E905057CQ50143303-9D5C5B87-354B-499E-B167-86DA88D21094Q50212262-A19E1008-74B6-45C6-96A2-41FF69A263FBQ55048307-4652B7E8-294F-4742-BAAE-DF8B59725F3FQ55091270-98924094-57E6-4C83-9C00-5BBB2F0BAD75Q55155200-E9CE1C11-3ECF-401C-BF14-0204129564D5Q57404709-DF662140-0283-4343-9545-72E47ED81E29Q57404710-D211B58D-2EE6-4AE8-A71E-AD68E3BA7F6AQ58099267-A6C997BD-75A4-4FC0-A963-74320BF31B43
P2860
Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs).
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Towards medicinal mechanochemi ...... maceutical ingredients (APIs).
@en
type
label
Towards medicinal mechanochemi ...... maceutical ingredients (APIs).
@en
prefLabel
Towards medicinal mechanochemi ...... maceutical ingredients (APIs).
@en
P2860
P356
P1476
Towards medicinal mechanochemi ...... maceutical ingredients (APIs).
@en
P2093
Leigh Loots
P2860
P304
P356
10.1039/C6CC02015A
P407
P577
2016-05-17T00:00:00Z