INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC.

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PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.

P2860

Q47100426-0080FF06-9BC2-4655-850B-39C7B587C93B

P2860

INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC.

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http://www.wikidata.org/entity/Q38961647

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

@zh-hk

2017年論文

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2017年論文

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2017年论文

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2017年论文

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2017年论文

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INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC.

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type

Item

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INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC.

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INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC.

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P1476

INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC.

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P2093

Darien E Reed

http://www.w3.org/2001/XMLSchema#string

Kevan M Shokat

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P2860

Purification and characterization of phosphoinositide 3-kinase from rat liver

The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer

Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Molecular portraits of human breast tumours

RNA-programmed genome editing in human cells

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

Triple-negative breast cancer: an unmet medical need

Exploiting the PI3K/AKT pathway for cancer drug discovery

PI3K pathway alterations in cancer: variations on a theme

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765-775

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scholarly article

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10.1158/1541-7786.MCR-16-0183

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http://www.w3.org/2001/XMLSchema#string

P478

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2017-02-14T00:00:00Z

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28196852

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5502826

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INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC.

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P2860

P2860

INPP4B and PTEN Loss Leads to PI-3,4-P2 Accumulation and Inhibition of PI3K in TNBC.

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type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932