Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway.
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Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis.Post-treatment of melatonin with CCl4 better reduces fibrogenic and oxidative changes in liver than melatonin co-treatment.Mechanistic insight into contextual TGF-β signaling.Smad3-STAT3 crosstalk in pathophysiological contexts.TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer.Network of MicroRNAs Mediate Translational Repression of Bone Morphogenetic Protein Receptor-2: Involvement in HIV-Associated Pulmonary Vascular Remodeling.Expression patterns of STAT3, ERK and estrogen-receptor α are associated with development and histologic severity of hepatic steatosis: a retrospective study.TIM‑4 blockade of KCs combined with exogenous TGF‑β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts.Andrographolide Ameliorates Liver Fibrosis in Mice: Involvement of TLR4/NF-κB and TGF-β1/Smad2 Signaling Pathways.S-allyl-cysteine attenuates carbon tetrachloride-induced liver fibrosis in rats by targeting STAT3/SMAD3 pathway.STAT3 in Skeletal Muscle Function and Disorders
P2860
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P2860
Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年学术文章
@wuu
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
@zh
2017年學術文章
@zh-hant
name
Transforming Growth Factor-β ( ...... ination with the SMAD Pathway.
@en
type
label
Transforming Growth Factor-β ( ...... ination with the SMAD Pathway.
@en
prefLabel
Transforming Growth Factor-β ( ...... ination with the SMAD Pathway.
@en
P2093
P2860
P356
P1476
Transforming Growth Factor-β ( ...... dination with the SMAD Pathway
@en
P2093
Li-Rong Yu
Liu-Ya Tang
Mary Heller
Zhaojing Meng
P2860
P304
P356
10.1074/JBC.M116.773085
P407
P50
P577
2017-01-31T00:00:00Z