CYP3A4-dependent cellular response does not relate to CYP3A4-catalysed metabolites of C-1748 and C-1305 acridine antitumor agents in HepG2 cells.

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CYP3A4-dependent cellular response does not relate to CYP3A4-catalysed metabolites of C-1748 and C-1305 acridine antitumor agents in HepG2 cells.

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http://www.wikidata.org/entity/Q38988914

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2014 nî lūn-bûn

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

@zh-my

2014年学术文章

@zh-sg

2014年學術文章

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2014年學術文章

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2014年學術文章

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name

CYP3A4-dependent cellular resp ...... titumor agents in HepG2 cells.

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type

Item

label

CYP3A4-dependent cellular resp ...... titumor agents in HepG2 cells.

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prefLabel

CYP3A4-dependent cellular resp ...... titumor agents in HepG2 cells.

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P1476

CYP3A4-dependent cellular resp ...... titumor agents in HepG2 cells.

@en

P2093

Adam Hołownia

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P2860

Products of metabolic activation of the antitumor drug ledakrin (nitracrine) in vitro.

Pre-clinical toxicology and pathology of 9-(2'-hydroxyethylamino)-4-methyl-1-nitroacridine (C-1748), a novel anti-cancer agent in male Beagle dogs.

CYP3A4 overexpression enhances the cytotoxicity of the antitumor triazoloacridinone derivative C-1305 in CHO cells.

Induction of cytochrome P450 1A1 in MCF-7 human breast cancer cells by 4-chlorobiphenyl (PCB3) and the effects of its hydroxylated metabolites on cellular apoptosis

Cell-based systems to assess nuclear receptor activation and their use in drug development.

Prodrugs for improving tumor targetability and efficiency.

Moving towards individualized medicine with pharmacogenomics.

Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.

Drug metabolism and variability among patients in drug response.

Role of human UDP-glucuronosyltransferases in the biotransformation of the triazoloacridinone and imidazoacridinone antitumor agents C-1305 and C-1311: highly selective substrates for UGT1A10

P304

1291-1303

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P31

scholarly article

P356

10.1002/CBIN.10322

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Zofia Mazerska

Ewa Augustin

Magdalena Niemira

P577

2014-06-16T00:00:00Z

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P5875

262733614

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24890801

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