Curcumin modulates α-synuclein aggregation and toxicity. - sprookjes - yvandenbroek - TriplyDB

Curcumin modulates α-synuclein aggregation and toxicity.

Curcumin modulates α-synuclein aggregation and toxicity.

http://www.wikidata.org/entity/Q39178579

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Digested disorder: Quarterly intrinsic disorder digest (January/February/March, 2013).Plant-derived neuroprotective agents in Parkinson's disease Cuminaldehyde as the Major Component of Cuminum cyminum, a Natural Aldehyde with Inhibitory Effect on Alpha-Synuclein Fibrillation and Cytotoxicity Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system Inhibition of calpain prevents manganese-induced cell injury and alpha-synuclein oligomerization in organotypic brain slice cultures Curcumin Pyrazole and its derivative (N-(3-Nitrophenylpyrazole) Curcumin inhibit aggregation, disrupt fibrils and modulate toxicity of Wild type and Mutant α-Synuclein Curcumin alters the salt bridge-containing turn region in amyloid β(1-42) aggregates.Role of alpha-synuclein in autophagy modulation of primary human T lymphocytes Biochemical stabilization of glucagon at alkaline pH.Structure and mechanism of action of tau aggregation inhibitors.Familial Parkinson disease-associated mutations alter the site-specific microenvironment and dynamics of α-synuclein.Intracellular screening of a peptide library to derive a potent peptide inhibitor of α-synuclein aggregation.Cytotoxic helix-rich oligomer formation by melittin and pancreatic polypeptide Gelsolin Amyloidogenesis Is Effectively Modulated by Curcumin and Emetine Conjugated PLGA Nanoparticles.Site-Specific Fluorescence Polarization for Studying the Disaggregation of α-Synuclein Fibrils by Small Molecules.Cell Adhesion on Amyloid Fibrils Lacking Integrin Recognition Motif.Amyloid formation of growth hormone in presence of zinc: Relevance to its storage in secretory granules Curcumin: A multi-target disease-modifying agent for late-stage transthyretin amyloidosis.Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species.Natural polyphenols binding to amyloid: a broad class of compounds to treat different human amyloid diseases.Proteomic analysis of Nipponia nippon (ID#162).α-Synuclein aggregation modulation: an emerging approach for the treatment of Parkinson's disease.Natural product-based amyloid inhibitors.Structure based aggregation studies reveal the presence of helix-rich intermediate during α-Synuclein aggregation.Curcumin homing to the nucleolus: mechanism for initiation of an apoptotic program.Studies to reveal the nature of interactions between catalase and curcumin using computational methods and optical techniques.Glycerol inhibits the primary pathways and transforms the secondary pathway of insulin aggregation.Effect of curcumin analogs onα-synuclein aggregation and cytotoxicity.Tau-derived-hexapeptide 306VQIVYK311 aggregation inhibitors: nitrocatechol moiety as a pharmacophore in drug design Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments.Juglanin inhibits lung cancer by regulation of apoptosis, ROS and autophagy induction.Inhibitory effects of curcumin and cyclocurcumin in 1-methyl-4-phenylpyridinium (MPP+) induced neurotoxicity in differentiated PC12 cells.p53 amyloid formation leading to its loss of function: implications in cancer pathogenesis.Turmeric effect on subcutaneous insulin-induced amyloid mass: an in vivo study.Inhibition of Prion Propagation by 3,4-Dimethoxycinnamic Acid.Effect of curcumin on amyloid-like aggregates generated from methionine-oxidized apolipoprotein A-I.Unravelling the inhibitory activity of Chlamydomonas reinhardtii sulfated polysaccharides against α-Synuclein fibrillation.Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates.Tuning the Balance between Fibrillation and Oligomerization of α-Synuclein in the Presence of Dopamine

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P2860

Curcumin modulates α-synuclein aggregation and toxicity.

http://www.wikidata.org/entity/Q39178579

description

2012 nî lūn-bûn

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Curcumin modulates α-synuclein aggregation and toxicity.

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Curcumin modulates α-synuclein aggregation and toxicity.

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type

label

Curcumin modulates α-synuclein aggregation and toxicity.

@en

Curcumin modulates α-synuclein aggregation and toxicity.

@nl

prefLabel

Curcumin modulates α-synuclein aggregation and toxicity.

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Curcumin modulates α-synuclein aggregation and toxicity.

@nl

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ACS Chemical Neuroscience

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Curcumin modulates α-synuclein aggregation and toxicity

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Ashutosh Kumar

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Dhiman Ghosh

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Ganesh M Mohite

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Pradeep K Singh

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Vasudha Kotia

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P2860

REVIEW: Curcumin and Alzheimer's Disease

Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity

Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds

Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation

Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models

The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds

Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism

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393-407

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10.1021/CN3001203

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3

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4

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23509976

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3605819

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