The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.
about
Molecular Mechanisms of Obesity-Induced Osteoporosis and Muscle AtrophyInfluenza a virus host shutoff disables antiviral stress-induced translation arrestFormal ring-opening/cross-coupling reactions of 2-pyrones: iron-catalyzed entry into stereodefined dienyl carboxylates.STAT3 promotes IFNγ/TNFα-induced muscle wasting in an NF-κB-dependent and IL-6-independent manner.Rejuvenation of the muscle stem cell population restores strength to injured aged muscles.The novel equisetin-like compound, TA-289, causes aberrant mitochondrial morphology which is independent of the production of reactive oxygen species in Saccharomyces cerevisiae.C26 cancer-induced muscle wasting is IKKβ-dependent and NF-kappaB-independent.UVC-induced stress granules in mammalian cellsA Key Role for Leukemia Inhibitory Factor in C26 Cancer Cachexia.Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexiaStaufen1 impairs stress granule formation in skeletal muscle cells from myotonic dystrophy type 1 patients.The eIF4AIII RNA helicase is a critical determinant of human cytomegalovirus replication.HuR and miR-1192 regulate myogenesis by modulating the translation of HMGB1 mRNAFlavaglines: potent anticancer drugs that target prohibitins and the helicase eIF4A.Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents.Sorafenib, a multikinase inhibitor, induces formation of stress granules in hepatocarcinoma cells.Synthesis of a simplified triazole analogue of pateamine A.Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation.Modeling human cancer cachexia in colon 26 tumor-bearing adult mice.Targeting RNA helicases in cancer: The translation trap.Gold Catalysis for Heterocyclic Chemistry: A Representative Case Study on Pyrone Natural Products.Stress granules counteract senescence by sequestration of PAI-1.Concise Synthesis of a Pateamine A Analogue with In Vivo Anticancer Activity Based on an Iron-Catalyzed Pyrone Ring Opening/Cross-Coupling.eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways.The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting.
P2860
Q28072006-4EA4FFA4-E063-4721-9BAB-DF06FD947084Q28540648-DD3F05CD-2D28-4740-88EE-5D4863FF7889Q30486419-190598DE-79A0-48E6-A7AD-8DFACA952036Q33626190-128EE1EF-A868-47F8-9219-903385AA9FD0Q34404503-C2E68041-CD27-421F-9399-E2224D0249D9Q34743426-D79DCA66-F412-4A6E-B311-5AF8C264F1C4Q35086723-01FACE0D-BBCE-4CFF-B6BF-167FCF7C2BF9Q35435960-D8363DD9-BAAD-4C06-9906-8EAF25E29445Q35925919-AFBD8304-4067-40C5-A6BE-8370F808140FQ36934990-1AA509C8-E54F-4255-9A6F-A572320E19E2Q36944554-531E5397-432F-40A6-896A-72846A6B2E7FQ37003223-6A245A52-A568-402A-8242-E11F6C230666Q37734542-4878EBFA-811D-4006-875A-2FC153D75008Q38164843-7A915055-0CD0-4B26-96AC-1F0038F01D60Q38346557-790A3092-01B2-495F-9DAB-EB4E1889A468Q38820303-50D314D6-0866-460E-ACB9-9959DDFFF5DDQ39328875-F8BEE1F0-F0C5-4DB1-A9F0-D9F90A398A76Q41888766-02D723A0-79B5-44E3-B5D6-CA7E0E56FDB6Q42229082-2974E900-06A2-4132-8880-AFB0A5E79371Q47719079-4FA54D37-F33C-4DA3-8741-AEF37B63FD93Q48141113-0D537E32-F0C8-4334-B38A-A4F349F2FDE3Q51758735-AA4B9D78-77E0-4272-9965-9FEBA27205B0Q53126778-0BCDC403-9B94-4AF4-A550-A3379607B03DQ54959711-E244D879-611B-4DFF-9D4C-D9879E21D783Q55653938-953399CA-9C94-4183-AD18-5D5EA3D857E5
P2860
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.
@en
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.
@nl
type
label
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.
@en
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.
@nl
prefLabel
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.
@en
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.
@nl
P2093
P2860
P356
P1476
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice.
@en
P2093
Anne Cammas
Derek T Hall
Erzsebet Nagy Kovacs
Imed Eddine Gallouzi
Jennifer F Ma
Jerry Pelletier
John Richardson
Rachid Mazroui
Sergio Di Marco
Xian Jin Lian
P2860
P2888
P356
10.1038/NCOMMS1899
P407
P577
2012-06-12T00:00:00Z