Regulation of translation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53.
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eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagyRequirement for the eIF4E binding proteins for the synergistic down-regulation of protein synthesis by hypertonic conditions and mTOR inhibitionHyperglycemia-induced O-GlcNAcylation and truncation of 4E-BP1 protein in liver of a mouse model of type 1 diabetes.Ischemia-induced calpain activation causes eukaryotic (translation) initiation factor 4G1 (eIF4GI) degradation, protein synthesis inhibition, and neuronal deathInsights into 4E-BP1 and p53 mediated regulation of accelerated cell senescenceBaculovirus DNA replication-specific expression factors trigger apoptosis and shutoff of host protein synthesis during infectionp53, a translational regulator: contribution to its tumour-suppressor activity.4E-BP1 regulates the sensitivity of human glioma cells to chemotherapy through PI3K/Akt/mTOR-independent pathway.Possible novel roles of poly(rC)-binding protein 1 in SH-SY5Y neurocytes: an analysis using a dynamic Bayesian network.Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas.Activation of p53 stimulates proteasome-dependent truncation of eIF4E-binding protein 1 (4E-BP1).Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture.Roles of the translationally controlled tumour protein (TCTP) and the double-stranded RNA-dependent protein kinase, PKR, in cellular stress responses.Role of ERK/mTOR signaling in TGFbeta-modulated focal adhesion kinase mRNA stability and protein synthesis in cultured rat IEC-6 intestinal epithelial cells.The p53 target gene TRIM22 directly or indirectly interacts with the translation initiation factor eIF4E and inhibits the binding of eIF4E to eIF4G.Effects of protein phosphorylation on ubiquitination and stability of the translational inhibitor protein 4E-BP1.Translation Control by p53.40 Years of Research Put p53 in Translation.
P2860
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P2860
Regulation of translation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Regulation of translation fact ...... thesis from inhibition by p53.
@en
Regulation of translation fact ...... thesis from inhibition by p53.
@nl
type
label
Regulation of translation fact ...... thesis from inhibition by p53.
@en
Regulation of translation fact ...... thesis from inhibition by p53.
@nl
prefLabel
Regulation of translation fact ...... thesis from inhibition by p53.
@en
Regulation of translation fact ...... thesis from inhibition by p53.
@nl
P2860
P356
P1476
Regulation of translation fact ...... thesis from inhibition by p53.
@en
P2093
Clemens MJ
Constantinou C
P2860
P2888
P304
P356
10.1038/SJ.CDD.4402045
P577
2006-09-22T00:00:00Z
P5875
P6179
1031636700